[HTML][HTML] Update of Indoles: Promising molecules for ameliorating metabolic diseases
W Hu, G Yan, Q Ding, J Cai, Z Zhang, Z Zhao… - Biomedicine & …, 2022 - Elsevier
… Among all kinds of alkaloids, indole alkaloids, related to the … Indole alkaloids are generally
extracted from the plant … As pharmacologically active secondary metabolites, indole alkaloids …
extracted from the plant … As pharmacologically active secondary metabolites, indole alkaloids …
Research progress of indole compounds with potential antidiabetic activity
Y Zhu, J Zhao, L Luo, Y Gao, H Bao, P Li… - European Journal of …, 2021 - Elsevier
… indole alkaloids to screen their antidiabetic activities. In this present review, we focus on indole
alkaloids … Recently, PPARα and PPARγ had been identified to be the therapeutic targets …
alkaloids … Recently, PPARα and PPARγ had been identified to be the therapeutic targets …
Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers
F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
… It is significant to highlight that thorough SAR investigations help to optimize the biological
activities of these marine indole alkaloids for possible therapeutic applications by offering …
activities of these marine indole alkaloids for possible therapeutic applications by offering …
An insight in anti-malarial potential of indole scaffold: A review
… This enzyme can be inhibited by Apicidin which is an indole alkaloid [5]. Malaria along with
being widely prevalent has become a grave problem due to the evolution of drug resistant …
being widely prevalent has become a grave problem due to the evolution of drug resistant …
[HTML][HTML] Marine-derived indole alkaloids and their biological and pharmacological activities
… This review reports the indole alkaloids isolated during the … indole alkaloids reported from
2016 to 2021 were collected from various scientific databases. A total of 186 indole alkaloids …
2016 to 2021 were collected from various scientific databases. A total of 186 indole alkaloids …
Potential therapeutic applications of plant‐derived alkaloids against inflammatory and neurodegenerative diseases
… possible therapeutic targets to suppress the inflammatory pathogenesis of diseases. Figure
3 illustrates the mechanism of alkaloids … Among monoterpene indole alkaloids extracted from …
3 illustrates the mechanism of alkaloids … Among monoterpene indole alkaloids extracted from …
[HTML][HTML] Anti-Alphaviral Alkaloids: Focus on Some Isoquinolines, Indoles and Quinolizidines
AL Sandenon Seteyen, E Girard-Valenciennes… - Molecules, 2022 - mdpi.com
… potential in multifactorial chronic health conditions including immunological, metabolic and
neurologic disorders [55]. Indole alkaloids … predominant monoterpene indole alkaloids which …
neurologic disorders [55]. Indole alkaloids … predominant monoterpene indole alkaloids which …
Indole and indoline scaffolds in drug discovery
F Liu, M Su - Privileged Scaffolds in Drug Discovery, 2023 - Elsevier
… Nortopsentins A–C (Nortopsentins D) (4) as indole alkaloids were isolated from Spongosorites
ruetzleri and showed in vitro cytotoxicity against P388 lymphocytic leukemia cells (IC 50 , …
ruetzleri and showed in vitro cytotoxicity against P388 lymphocytic leukemia cells (IC 50 , …
Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications
S Fernández, V Arnáiz, D Rufo, Y Arroyo - Marine Drugs, 2024 - mdpi.com
… and functional versatility of indole alkaloid derivatives spots them as … potential applications
in drug discovery. Therefore, the purpose of this review is to exclusively cover indole alkaloid …
in drug discovery. Therefore, the purpose of this review is to exclusively cover indole alkaloid …
Indoleamine and tryptophan 2, 3-dioxygenases as important future therapeutic targets
… , IDOs and TDO represent important targets for therapeutic intervention. This pathway has
… This review summarizes recent advances on IDO and TDO as potential drug targets, and …
… This review summarizes recent advances on IDO and TDO as potential drug targets, and …