The role of exosomes and miRNAs in drug‐resistance of cancer cells

DH Bach, JY Hong, HJ Park… - … journal of cancer, 2017 - Wiley Online Library
cancer cells may also confer chemotherapy and radiation therapy resistance.129 Exosomes
… from target cancer cells.130, 131 BM-MSC-derived exosomes induce multiple myeloma …

Role of hypoxia-induced exosomes in tumor biology

C Shao, F Yang, S Miao, W Liu, C Wang, Y Shu… - Molecular Cancer, 2018 - Springer
… in an HIF-dependent manner, which stimulate invasion and metastasis by contacting with
recipient cancer cells [31]. In the present review, we will discuss how exosomes induced by …

Bladder cancer cell-derived exosomes inhibit tumor cell apoptosis and induce cell proliferation in vitro

L Yang, XH Wu, D Wang… - Molecular medicine …, 2013 - spandidos-publications.com
… ‑to‑cell signaling. This study aimed to investigate the effects of bladder cancer cell‑derived
exosomes on the regulation of tumor cellExosomes were purified from the supernatants of …

Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration

X Zhang, H Shi, X Yuan, P Jiang, H Qian, W Xu - Molecular cancer, 2018 - Springer
… this study that exosomes from human gastric cancer cells induced neutrophils to represent
an N2-like phenotype, supporting a role of tumor-derived exosomes in neutrophil polarization. …

The role of cancer-derived exosomes in tumorigenicity & epithelial-to-mesenchymal transition

RH Blackwell, KE Foreman, GN Gupta - Cancers, 2017 - mdpi.com
… was induced, while exosome-depleted cancer cell culture … stimulation of exosome release
from melanoma cells in vitro … with cancer-derived exosomes isolated from breast cancer cell

Exosomes derived from pancreatic cancer cells induce activation and profibrogenic activities in pancreatic stellate cells

A Masamune, N Yoshida, S Hamada… - Biochemical and …, 2018 - Elsevier
… in the exosome-mediated interactions between PCCs and PSCs. In conclusion, we showed
that PCC-derived exosomes induce the … by which PCCs develop a cancer-conditioned tumor …

Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting …

JA Cho, H Park, EH Lim, KH Kim, JS Choi, JH Lee… - Gynecologic …, 2011 - Elsevier
… breast cancer cell-derived exosomes in … cancer-derived exosomes presents a new potential
role and importance of tumor-derived exosomes, suggesting that tumor-derived exosomes

Senescence-associated exosome release from human prostate cancer cells

BD Lehmann, MS Paine, AM Brooks, JA McCubrey… - Cancer research, 2008 - AACR
… We show here that this treatment-induced senescence was … the induction of p53-dependent
senescence and the release of endosome-derived exosomes in human prostate cancer cells

Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells

KE Richards, AE Zeleniak, ML Fishel, J Wu… - Oncogene, 2017 - nature.com
… Having shown that chemotherapy treatment of CAFs causes the increased secretion of
chemoresistance-inducing exosomes, and increased cell survival, we next assessed whether …

Exosomes induce fibroblast differentiation into cancer-associated fibroblasts through TGFβ signaling

C Ringuette Goulet, G Bernard, S Tremblay… - Molecular Cancer …, 2018 - AACR
… whether exosomes produced by bladder cancer cells could … exosomal TGFβ is sufficient
to induce CAF differentiation, we assessed the capacity of proteinase K treated exosomes to …