… Sema7A expressed on activated T cells stimulates macrophages through α1β1 integrin to
promote inflammatory responses. Sema7A also binds to plexin-C1 to induce monocyte and …

… Semaphorins and plexins have also been found to control … semaphorins and plexins
have crucial roles in inflammatory … , and semaphorin 3A and inhibitors of semaphorin-4D-induced …

… to TLR agonist–induced inflammation and polymicrobial peritonitis caused by cecal ligation
… a ligand of plexin-A4, Sema3A (semaphorin 3A), exacerbates the cytokine storm caused by …

… Additionally, we aimed to demonstrate the necessity of Plexin-A1 for the optimal production
of inflammatory mediators following stimulation of the TLR4 pathway in BV-2 cells. In this …

… , semaphorin 3A is structurally similar to its receptor plexin … In this case, semaphorin 3A
signaling primarily induces the … effects of semaphorin 3A on inflammatory cytokine production …

… This finding might be explained simply by the fact that the percentage of CD4+ T cells
expressing plexin D1 is much higher than those expressing plexin B2 and NRP-1, but we cannot …

… In pre-clinical rat models, we show that the semaphorin-plexin pathway represents a new …
The effect of curcumin on acute kidney injury was associated with the semaphorin-plexin …

… 1) bind to virus-encoded semaphorin protein receptor (VESPR) (also known as plexin C1
and CD232) and induce the production of pro-inflammatory cytokines, thereby modulating the …

… to pro- or anti-inflammatory stimuli. The semaphorin-plexin axes in the presence or absence
of … In models of hypoxia-induced myocardial inflammation SEMA3A levels are decreased in …

… semaphorins (class VII). Some promiscuity could exist, with certain semaphorins binding
to several plexin families (eg plexin-… -A1 receptor in sensory neurons blocks Sema3A-induced …