过去一年中添加的文章,按日期排序

CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabolism alteration

Y Geng, X Zheng, D Zhang, S Wei, J Feng, W Wang… - Biology Direct, 2024 - Springer
86 天前 - … profiles between Cetuximab sensitive and resistant CRC … that can affect sensitivity
to Cetuximab treatment and … also reduced the sensitivity of tumors to Cetuximab in vivo…

DUSP4 loss enhances resistance to encorafenib plus cetuximab in BRAF mutant colorectal cancer

K Needham, F Chionh, S Kaczmarczyk, C Kearney… - Cancer Research, 2024 - AACR
132 天前 - … Dual-specificity phosphatase 4 (DUSP4) is rapidly induced upon … on sensitivity of
BRAF-mutant CRC cells to encorafenib+… DUSP4 knockdown also reduced sensitivity of BRAF …

Clinical Evaluation of the Effect of Encorafenib on Bupropion, Rosuvastatin, and Coproporphyrin I and Considerations for Statin Coadministration

J Piscitelli, MB Reddy, L Wollenberg, L Del Frari… - Clinical …, 2024 - Springer
154 天前 - … cause clinically relevant CYP2B6 induction or inhibition but is … Encorafenib in
combination with binimetinib or cetuximab … as it is considered a sensitive substrate of CYP2B6 and …

Dual anti-HER2/EGFR inhibition synergistically increases therapeutic effects and alters tumor oxygenation in HNSCC

PN Song, SE Lynch, CT DeMellier, A Mansur… - Scientific Reports, 2024 - nature.com
169 天前 - … through reductions in tumor hypoxia and induces … and induces a state of increased
radiation sensitivity in vivo, … -cetuximab decreases tumor hypoxia and can induce a state …

[HTML][HTML] Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion. Menu

E Kornelius, HH Li, CH Peng, HW Hsiao, YS Yang… - cetuximabinhibitor.com
225 天前 - reduce the number of p-tau aggregates induced by Aβ, … and insulin signaling
sensitivity in various organs including … Aβ-induced neurotoxicity by activating AMPK signaling. …

Chemoresistant fibroblasts dictate neoadjuvant chemotherapeutic response of head and neck cancer via TGFα-EGFR paracrine signaling

L Su, S Wu, C Huang, X Zhuo, J Chen, X Jiang… - NPJ Precision …, 2023 - nature.com
295 天前 - … primary CAFs isolated from chemo-sensitive (sCAFs) or -… chemotherapy-induced
apoptosis while reducing HNSCC … of cetuximab restored cancer cell sensitivity to cisplatin in …

Tumor Microenvironment Modulation by Cetuximab and its Contribution to Subsequent Immune-Checkpoint Inhibition Therapy in Recurrent/Metastatic Head and Neck …

K Okuyama, T Naruse, S Yanamoto - Journal of Oral and Maxillofacial …, 2023 - joms.org
335 天前 - … (EGFR) pathway, cetuximab-mediated EGFR … escape induction, and tumor
vessel perfusion by promoting CD8+ T-cell accumulation and IFN-g production in treatment-sensitive

Cetuximab-based PROteolysis targeting chimera for effectual downregulation of NSCLC with varied EGFR mutations

R Vartak, B Deore, CA Sanhueza, K Patel - International Journal of …, 2023 - Elsevier
348 天前 - … 30 folds reduction in IC 50 was observed with ABTAC in HCC827 (EGFR sensitive)
and … Multicellular 3D spheroid assay strongly suggested that ABTAC induced significant …