Induction of apoptosis by cancer chemotherapy

SH Kaufmann, WC Earnshaw - Experimental cell research, 2000 - Elsevier
… major cell-intrinsic pathways for inducing apoptosis, one that begins with ligation of cell
surface … Several reports have suggested that anticancer drugs kill susceptible cells by inducing

The induction of apoptosis by bacterial pathogens

Y Weinrauch, A Zychlinsky - Annual Reviews in Microbiology, 1999 - annualreviews.org
… Unlike Shigella spp., which must be internalized to induce cell death, yersiniae are able
to induce apoptosis from the outside of the host cells (163, 166). Upon contact with the host …

Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs

G Strauss, W Osen, KM Debatin - Clinical & Experimental …, 2002 - academic.oup.com
… MTX induced apoptosis in the Jurkat T cell line, peripheral human resting and activated T
cells … Interestingly, we found that CP induced apoptosis in activated as well as in resting T cell

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

Y Haupt, S Rowan, E Shaulian… - Genes & …, 1995 - genesdev.cshlp.org
… , we analyzed the ability of various p53 deletion mutants to induce apoptosis in HeLa cells.
We report here that a truncated polypeptide, containing only the first 214 residues (of 390) of …

Apoptolidin: Induction of apoptosis by a natural product

PT Daniel, U Koert, J Schuppan - … Chemie International Edition, 2006 - Wiley Online Library
… selectively induces apoptosis in several cancer cell lines. … ways to regulate, induce, and
execute cell death that show no … compounds to induce apoptosis in mammalian cells, since …

[HTML][HTML] Induction of apoptosis by the transcription factor c-Jun

E Bossy-Wetzel, L Bakiri, M Yaniv - The EMBO journal, 1997 - embopress.org
… transformation, recently has also been linked to apoptosis. To explore further the functional
… to trigger apoptotic cell death in NIH 3T3 fibroblasts. c-Jun-induced apoptosis is evident at …

Induction of apoptosis by c-Fos protein

GA Preston, TT Lyon, Y Yin, JE Lang… - … and Cellular Biology, 1996 - Am Soc Microbiol
… In this report, we show that the activated c-FosER protein induces apoptosis in sup II … v-Fos
is capable of inducing apoptosis in these cells. Sup I and sup II cells were cotransfected with …

Induction of apoptosis in mammalian cells by cadmium and zinc.

W Wätjen, H Haase, M Biagioli… - Environmental Health …, 2002 - ehp.niehs.nih.gov
induce cell death either by necrotic or by apoptotic mechanisms. This metal was shown to
induce apoptosis only in distinct cell … µM and above induced apoptosis in C6 glioma cells that …

Death receptor activation-induced hepatocyte apoptosis and liver injury

XM Yin, WX Ding - Current molecular medicine, 2003 - ingentaconnect.com
… One of the major bile acids, glycochenodeoxycholate (GCDC) is apparently able to induce
apoptosis in cultured primary hepatocytes in a Fas-dependent fashion [49]. Animal studies …

Induction of apoptosis and activation of NF‐κB by CD95 require different signalling thresholds

P Legembre, BC Barnhart, L Zheng, S Vijayan… - EMBO …, 2004 - embopress.org
… To further explore the relative requirement for a functional DD in inducing apoptosis
versus activating NF‐κB and MAP kinases, we studied splenocytes from C3H wt/wt , C3H wt/lpr(cg) …