Immune checkpoint blockade in infectious diseases

MN Wykes, SR Lewin - Nature Reviews Immunology, 2018 - nature.com
… treating a range of infectious diseases. Here, we review our current understanding of immune
checkpoint pathways in the pathogenesis of infectious diseases and discuss the potential …

Immune checkpoints and their inhibition in cancer and infectious diseases

L Dyck, KHG Mills - European journal of immunology, 2017 - Wiley Online Library
… NK cells also express immune checkpoints and this may compromise their protective role
in early immune responses against cancer and infectious diseases. Expression of PD-1 is …

Current progress and future perspectives of immune checkpoint in cancer and infectious diseases

X Cai, H Zhan, Y Ye, J Yang, M Zhang, J Li… - Frontiers in …, 2021 - frontiersin.org
immune checkpoints in cancer and infectious diseases. We also discuss the impact of the
bacterial microbiome on the relationship between cancer therapy and the immune system. …

Checkpoint inhibition and infectious diseases: a good thing?

MS Abers, MS Lionakis, DP Kontoyiannis - Trends in Molecular Medicine, 2019 - cell.com
… of several immune checkpoint molecules promotes antitumor immunity and increases … of
infection suggests that immune checkpoint molecules regulate the host immune responses to …

Check point inhibitors as therapies for infectious diseases

MA Cox, R Nechanitzky, TW Mak - Current Opinion in Immunology, 2017 - Elsevier
… This raises a conundrum, where inhibition of these checkpoints in patients could enhance …
to determine the impact of checkpoint blockade in the context of HIV infection. The majority of …

[HTML][HTML] Emerging concerns of infectious diseases in lung cancer patients receiving immune checkpoint inhibitor therapy

K Fujita, YH Kim, O Kanai, H Yoshida, T Mio, T Hirai - Respiratory Medicine, 2019 - Elsevier
… In this study, the term “infectious disease” was defined as infection requiring the … Infectious
disease related to immune checkpoint inhibitor was defined as infection occurring at any time …

Infectious complications in patients treated with immune checkpoint inhibitors

JD Karam, N Noel, AL Voisin, E Lanoy… - European Journal of …, 2020 - Elsevier
Immune checkpoint inhibitor (ICI) antibodies constitute a new generation of cancer treatments,
associated with immune-related adverse events (irAEs). A previous retrospective study of …

[HTML][HTML] … ) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Immune checkpoint inhibitors, cell adhesion …

G Redelman-Sidi, O Michielin, C Cervera, C Ribi… - … and Infection, 2018 - Elsevier
… This section is focused on the risk of infection entailed by the use immune checkpoint
inhibitors, cell adhesion inhibitors, sphingosine-1-phosphate (S1P) receptor modulators (fingolimod…

Infectious complications associated with the use of immune checkpoint inhibitors in oncology: reactivation of tuberculosis after anti PD-1 treatment

H Picchi, C Mateus, C Chouaid… - … and Infection, 2018 - clinicalmicrobiologyandinfection …
… All patients should probably be tested with an IGRA before the initiation of anti PD-1
treatment, and closer collaboration between infectious disease specialists and oncologists is …

[HTML][HTML] Anti-PD-1/PD-L1 therapy for infectious diseases: learning from the cancer paradigm

M Rao, D Valentini, E Dodoo, A Zumla… - … of Infectious Diseases, 2017 - Elsevier
… chronic infectious diseases. Immune checkpoint inhibition in infectious disease therapy
may be administered adjunctively to standard drug treatment − akin to cancer chemotherapy. …