Rabbit model of bacterial endocarditis

A Lefort, B Fantin - Handbook of animal models of infection, 1999 - Elsevier
Publisher Summary This chapter describes a rabbit model of bacterial endocarditis, in which
the white New Zealand female rabbits weighing 2–2.5 kg are the most commonly used. The …

Evaluation of antimicrobial agents in the rabbit model of endocarditis

MA Sande - Reviews of infectious diseases, 1981 - academic.oup.com
… in the heart of a rabbit results in nonbacterial thrombotic endocarditis characterized by an …
vegetations typical of infective endocarditis. In the rabbit model, endocarditis induced by …

Comparison of a rabbit model of bacterial endocarditis and an in vitro infection model with simulated endocardial vegetations

E Hershberger, EA Coyle, GW Kaatz… - Antimicrobial agents …, 2000 - Am Soc Microbiol
… The result of this study indicates the in vitro model to be comparable to the rabbit model
of endocarditis for study of the activity of fluoroquinolones. However, studies with other …

Aggregation and Binding Substances Enhance Pathogenicity in Rabbit Models of Enterococcus faecalis Endocarditis

PM Schlievert, PJ Gahr, AP Assimacopoulos… - Infection and …, 1998 - Am Soc Microbiol
We investigated the importance of enterococcal aggregation substance (AS) and enterococcal
binding substance (EBS) in rabbit models of Enterococcus faecalis cardiac infections. First…

The optimal aminoglycoside and its dosage for the treatment of severe Enterococcus faecalis infection. An experimental study in the rabbit endocarditis model

L Dubé, J Caillon, C Jacqueline, D Bugnon… - European journal of …, 2012 - Springer
Aminoglycosides are recommended for the treatment of Enterococcus faecalis infections,
especially in severe and bacteremic infection. However, the optimal aminoglycoside or the …

A new model for infective endocarditis of the mitral valve in rabbits

K Imataka, Y Kitahara, S Naito, J Fujii - American Heart Journal, 1993 - Elsevier
… of rabbits, we produced experimental infective endocarditis by bacterial inoculation alone. …
animal model of infective endocarditis as a counterpart of the human disease. This model was …

Rat model of experimental endocarditis

J Santoro, ME Levison - Infection and Immunity, 1978 - Am Soc Microbiol
… A simple model of infective endocarditis was produced in rats… DISCUSSION The rabbit
model of bacterial endocarditis has … of left-sided endocarditis on the aortic valve of rabbits using …

Notes on the early history of infective endocarditis and the development of an experimental model

A Contrepois - Clinical infectious diseases, 1995 - academic.oup.com
… in vegetations and cardiac valves of patients with endocarditis was first put forth by Winge
in … , an animal model of experimental endocarditis in which the aortic valves of rabbits were …

Antibodies to a Surface-Exposed, N-terminal Domain of Aggregation Substance Are Not Protective in the Rabbit Model of Enterococcus faecalis Infective Endocarditis

JK McCormick, H Hirt, CM Waters, TJ Tripp… - Infection and …, 2001 - Am Soc Microbiol
… immunity against endocarditis. In the rabbit model of experimental endocarditis, we used a
… from the conjugative plasmid pCF10) to immunize rabbits, followed by challenge with Asc10-…

Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis

PM Sullam, AS Bayer, WM Foss… - Infection and …, 1996 - Am Soc Microbiol
… When tested in a rabbit model, animals inoculated with PS12 were significantly less likely
to develop endocarditis and had lower densities of organisms (CFU per gram) within …