… by which the activation of NLRP3 inflammasomes affects the pathogenesis of … activation of
NLRP3 inflammasomes. By researching the activation or inactivation of NLRP3 inflammasome…

… disease. In the current review, we summarize the generally accepted mechanisms of NLRP3
inflammasome activation … of microglia-specific NLRP3 activation in AD pathogenesis, and …

… observed in Alzheimer patient brains. Inhibition of inflammasome activation just begins to …
models of Alzheimer's disease, thereby opening a new avenue for therapeutic intervention. …

… effects of NLRP3 inflammasome activation, and the study on inflammasome-dependent
pyroptosis … This study further supports that targeting NLRP3 inflammasome activation may offer a …

… The basic components of inflammasomes include a NOD-like receptor (NLR) that recognizes
danger signals or ligands, and procaspase-1 which is central to inflammasome activation. …

… However, the mechanism of NLRP1 inflammasome activation in AD is particularly elusive,
given its structural and functional complexities. In this review, we examine the implications of …

… activation of at least two different inflammasome complexes explains AD-associated
neuroinflammation. Strategies targeting inflammasome activation … inflammasome activation and …

… inflammasome activation of the innate immune response. The inflammasome is a multi-protein
complex that activates … (IL)-1β and IL-18 upon activation of caspase-1, resulting in the cell …

… mechanisms of the NLRP3 inflammasome in the pathogenic mechanisms of AD. … inflammasome
for AD. Further clarification of the regulatory mechanisms of the NLRP3 inflammasome …

… inflammasome activation … activation and resultant inflammasome assembly (Figure 1) as
discussed in detail in a recent review [2]. In the context of NLRP3 inflammasome activation …