… A streptozotocin-dependent model of diabetic kidney disease was used in the current
study. Persistent hyperglycemia was induced by intraperitoneal administration of 60 mg/kg …

… The results indicate that ASC as a NLRP3 inflammasome component can mediate ERK
activation through NLRP3 inflammasome activation [94]. During the progression of DKD, …

… Although inflammasome plays a well-known role in animal models of renal … kidney disease
(DKD) remains unknown. Aim of this study was to elucidate the contribution of inflammasome …

… inflammasome activation is increasingly recognised to play a key causative role in the
pathogenesis of several chronic kidney diseases in … role of the inflammasome in kidney injury has …

… Inflammasome activation not only amplifies renal inflammation but also has a role in the
development of fibrosis; pharmacological agents that target inflammasome components may …

… of the effects and regulation of inflammasomes during renal fibrosis. … inflammasome functions
during various kidney diseases, and these findings indicate that the NLRP3 inflammasome …

… In this study, we first examined a range of pyroptosis markers and inflammasome component
proteins in diabetic kidneys to investigate whether pyroptosis could occur in podocytes …

… related chronic diseases. Consequently, research on the NLRP3 inflammasome has …
investigated the role of NLRP3 activation in chronic kidney disease (CKD), few studies have …

… Activate AIM2 inflammasome signaling pathway Kidney injury leads to tubular cell
necrosis and the release of DNA, which is taken up by neighboring macrophages, the AIM2 …

… of BP patients included in our study may develop renal disease in the future, and these
patients may already carry undiagnosed signs of kidney disease at a very early stage. On that …