… in modulating IL-1β and inflammation, showing that caspase-8 directly regulates IL-1β
independent of inflammasomes or indirectly through the regulation of inflammasomes, depending …

… IL-1β processing via caspase-8 recruited to … inflammasomes recruit caspase-8 to drive IL-1β
processing in murine bone marrow-derived dendritic cells (BMDC) independent of caspase-…

… regulation of the FADD-caspase-8-cFLIP complex in cell death and … -cell death pathways
with a particular focus on caspase-8. … , caspase-8 is able to regulate the NLRP3 inflammasome …

… Our results provide a comprehensive analysis of the NLRP3 inflammasome pathways
activated by dsRNA and provide the first example of signalling by the FADD–caspase-8 complex …

… We then hypothesized that TLR4-induced inflammasome activation may be mediated by
caspase-8 signaling in retinal ischemia. The caspase-8 inhibitor Z-IETD-FMK-fmk was injected …

… of the role of caspase-8 in the regulation of inflammation, eg, inflammasome activation, IL-1β …
Caspase-8 is able to regulate NLRP3 inflammasome activation upstream of NLRP3 under …

… inflammasome and inflammatory cell death in the form of PANoptosis. Deleting NLRP3
inflammasome … a robust increase in the incidence of caspase-8– and receptor-interacting serine/…

… NLRP3 inflammasome, we examined its effect on caspase-1 … with robust nigericin-induced
caspase-1 processing (Fig. 1B) … of LPS mattered in regulating the NLRP3 inflammasome, we …

… of inflammasomes. In this review, we provide an overview of the latest development of
inflammasome research and discuss how inflammasome … covering Inflammasomes appearing in …

… 3 (NLRP3) inflammasome with caspase 8 in the … inflammasome and caspase 8 is fundamental
in our understanding of the inflammasomes and alternative modes of IL-1β regulation in …