… Therefore, inflammation can underlie atrial fibrosis; the … In addition, the inflammasome,
an intracellular inflammatory … about inflammation and fibrosis in the pathophysiology of AF, …

… In pressure-overloaded mice, atrial mast cell recruitment is responsible for atrial
inflammation and fibrosis through a platelet-dependent growth factor-A-related mechanism. …

… Mast cells might actively induce inflammation and atrial fibrosis in patients with AF and
secrete platelet-derived growth factor A (PDGF-A) and promote cell proliferation and collagen …

… The pathophysiology of atrial remodeling is very complex, and the molecular … fibrotic atrial
cardiomyopathy.5 Recently, the role of pathophysiologic pathways that involve inflammatory …

… inflammation and fibrosis as determinants of AF. Moreover, we will recapitulate current findings
on the role of serine proteases in the pathogenesis … of cardiac inflammation and fibrosis. …

… The pathophysiology of atrial fibrillation (AF) remains incompletely understood, despite its …
Recent evidence suggests that atrial fibrosis is linked not only to stimulation of myocytes and …

… pathophysiological significance of cardiomyocyte NLRP3 signalling in AF. We first summarize
the evidence for a role of inflammation in … in studies of classic inflammation. We then briefly …

… stimulants to tissue-fibrosis, acting via downstream systems like mitogen-activated protein
kinases 98 and NLRP3-inflammasome formation and profibrotic inflammatory signaling. All of …

… AF and inflammation, the inflammatory molecules … , inflammation plays an important role
in the vicious spiral through various inflammatory molecules, inflammatory cells, and fibrosis. …

… and oxidative stress are partially known for their involvement in the pathogenesis of AF (8). …
involves in AF pathophysiology. In particular, our review will summarize the effects of fibrosis, …