Inflammation and fibrosis in murine models of heart failure

L Bacmeister, M Schwarzl, S Warnke, B Stoffers… - Basic research in …, 2019 - Springer
… As evidence exists that cardiac inflammation and fibrosis are … heart failure treatments. In this
context, animal models are important as they mimic clinical conditions of heart failure patients…

Role of inflammation in heart failure

LF Shirazi, J Bissett, F Romeo, JL Mehta - Current atherosclerosis reports, 2017 - Springer
inflammatory cytokines, immune cells, and heart failure (HF). The association of heart failure
with inflammation … cardiac fibrosis [24, 25], while inhibiting inflammatory cytokine production. …

Markers of fibrosis, inflammation, and remodeling pathways in heart failure

C Passino, A Barison, G Vergaro, A Gabutti… - Clinica Chimica …, 2015 - Elsevier
Inflammation, fibrosis, neuro-hormonal activation, and ongoing myocardial damage are
the … in patients after a myocardial infarction or with heart failure. For this reason, there is an …

From systemic inflammation to myocardial fibrosis: the heart failure with preserved ejection fraction paradigm revisited

WJ Paulus, MR Zile - Circulation research, 2021 - Am Heart Assoc
… , and predictions involving inflammation markers in heart failure with a … , inflammatory
biomarkers, and echocardiographic cardiac function. Associations (red) between inflammatory

Fibrosis and heart failure

AM Segura, OH Frazier, LM Buja - Heart failure reviews, 2014 - Springer
… concepts of fibrosis as a main component of ventricular remodeling in heart failure patients.
Our … Inflammation is considered an important factor in the pathogenesis and progression of …

Mechanisms of cardiac fibrosis in inflammatory heart disease

G Kania, P Blyszczuk, U Eriksson - Trends in cardiovascular medicine, 2009 - Elsevier
… and fibrosis, promoting heart failure development. Dilated cardiomyopathy is an important
cause of heart failure … Monocytes and monocyte-like cells represent a major subset of heart-…

Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level

M Rao, X Wang, G Guo, L Wang, S Chen, P Yin… - Basic research in …, 2021 - Springer
… understand phenotypic alterations in severely fibrotic and inflamed heart. Hopefully, this
comprehensive single-cell map of human heart failure with profound resolution in immune cell …

Chronic heart failure and inflammation: what do we really know?

SA Dick, S Epelman - Circulation research, 2016 - Am Heart Assoc
… of chronic heart failure (HF). There is a wealth of information about the role of inflammatory
… and how the sum of initial inflammatory and reparative responses only sets the trajectory for …

Molecular imaging of inflammation and fibrosis in pressure overload heart failure

A Glasenapp, K Derlin, M Gutberlet, A Hess… - Circulation …, 2021 - Am Heart Assoc
… , but imbalance in the adaptive response can lead to heart failure. In this study, we characterize
the temporal inflammatory and fibrotic response to pressure overload using multimodality …

Systemic inflammation in heart failure–the whys and wherefores

A Yndestad, J Kristian Damås, E Øie, T Ueland… - Heart failure …, 2006 - Springer
heart failure (HF) are characterized by systemic inflammation, as evident by raised circulating
levels of several inflammatory … can contribute to this inflammation, including leukocytes, …