… inflammatory site, with no specific solid organ focus. Here we aimed to study the local
inflammatory response in organs using a porcine model of fulminant meningococcal septic shock …

… the pathogenesis of sepsis. Clinical trials with anti-inflammatory agents in patients with sepsis
… -γ, which, according to animal models of septic shock, presumably play a crucial role in the …

… Sepsis has been defined as the systemic inflammatory response that develops in response
to a documented infection.9, 11 Severe sepsis and septic shock … in the systemic inflammatory …

… the inflammatory response is intended to eliminate the invading micro-organisms, it may
overwhelm counterregulatory mechanisms, causing sepsis to deteriorate into septic shock, …

… Recent advances in our understanding of innate immunity, and the interaction between the
inflammatory and the haemostatic cascades, are affording new opportunities for therapeutic …

… therapies targeting the inflammatory response to sepsis. Recently, … pathogenesis of sepsis.
Activated protein C (APC), an endogenous protein that inhibits thrombosis and inflammation …

… and shock (eg, the release of inflammatory mediators). Since infection and sepsis did not …
Disturbances of selected plasma proteins in hyperdynamic septic shock. Intensive Care Med…

… The mechanisms involved in shock and organ injury induced in septic shock are … of
inflammation and cellular damage have been implicated in the pathogenesis of septic shock and …

… published data on the mechanisms of septic shock development obtained in various in vitro
… accounting for resis tance or sensitivity to septic shock in mouse models. Special attention …

… H 2 O 2 can also activate nuclear factor-κB (NF-κB) contributing to the inappropriate
activation of this master pro-inflammatory transcription factor observed in septic shock. The …