Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264. 7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO …

C Guo, L Yang, J Luo, C Zhang, Y Xia, T Ma… - International …, 2016 - Elsevier
… -inflammatory studies about Sophora alopecuroides focused … resources from Sophora
alopecuroides. Nevertheless, in vivo … of SG as a therapeutic agent to treat inflammatory diseases. …

Sophora alopecuroides L.: An ethnopharmacological, phytochemical, and pharmacological review

R Wang, X Deng, Q Gao, X Wu, L Han, X Gao… - Journal of …, 2020 - Elsevier
alopecuroides has prominent bioactivities, especially on gynecological inflammation and
hepatitis B, and anticancer activities. These activities provide prospects for novel drug …

Structurally Diverse Matrine‐Based Alkaloids with Anti‐inflammatory Effects from Sophora alopecuroides

D Luo, NH Chen, WZ Wang, JH Zhang… - Chinese Journal of …, 2021 - Wiley Online Library
… A phytochemical investigation on the seeds of Sophora alopecuroides led to obtaining … 1,
and MCF-7) and anti-inflammatory activities for two pro-inflammatory cytokines (TNF-α and IL-6)…

Aloperine suppresses LPS-induced macrophage activation through inhibiting the TLR4/NF-κB pathway

Y Ye, Y Wang, Y Yang, L Tao - Inflammation Research, 2020 - Springer
… and seeds of Sophora alopecuroides L. However, the anti-inflammatory effects of Aloperine
… Aloperine suppresses LPS-induced inflammatory responses in RAW264.7 macrophages. …

Undescribed matrine-type alkaloids from Sophora alopecuroides with anti-inflammatory activity

D Luo, JW Zou, JH Wang, H Tian, HY Xie, TX Zhu… - Phytochemistry, 2024 - Elsevier
alopecuroides was performed to obtain 12 previously undescribed matrine-type alkaloids (1…
) were evaluated for anti-inflammatory effect in the LPS-activated RAW264.7 cell model, anti-…

Anti-neuroinflammatory effect of Sophoraflavanone G from Sophora alopecuroides in LPS-activated BV2 microglia by MAPK, JAK/STAT and Nrf2/HO-1 signaling …

C Guo, L Yang, CX Wan, YZ Xia, C Zhang, MH Chen… - Phytomedicine, 2016 - Elsevier
Sophora alopecuroides is widely used in traditional Uighur's medicine for the treatment of
inflammation. Sophoraflavanone G (SG), a major flavonoid found in the S. alopecuroides, has …

Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

JC Li, WF Dai, D Liu, ZJ Zhang, MY Jiang, KR Rao… - Bioorganic …, 2021 - Elsevier
… of Sophora alopecuroides. Structurally, compounds 1–4 were the first examples of C-11
oxidized matrine-type alkaloids from Sophora … revealed its anti-inflammatory potential. Moreover, …

Evaluation of the wound healing potential of Sophora alopecuroides in SD rat's skin

X Sun, Y Yang, T Liu, H Huang, Y Kuang… - Journal of …, 2021 - Elsevier
… The results suggested that KDZ possessed significant anti-inflammatory action in LPS-induced
RAW264.7 cells without observable cytotoxicity. Subsequently, western blot analysis …

Alopecuroides A–E, Matrine-Type Alkaloid Dimers from the Aerial Parts of Sophora alopecuroides

CL Fan, YB Zhang, Y Chen, P Xie… - Journal of natural …, 2019 - ACS Publications
… in inflammation processes. To evaluate the bioactivities of compounds 1–5 on inflammation,
… As shown in Table 4, both of these pro-inflammatory cytokines were generated in RAW264.…

In vivo and in vitro anti-inflammatory effects of Sophora flavescens residues

H Ma, Q Huang, W Qu, L Li, M Wang, S Li… - Journal of …, 2018 - Elsevier
… of anti-inflammatory active ingredients. Our results showed that LPS-induced RAW264.7 cells
… or macrophages is the key pro-inflammatory cytokines in inflammatory process, it would be …