Role of pro-inflammatory cytokines in regulation of skeletal muscle metabolism: a systematic review

B Sharma, R Dabur - Current medicinal chemistry, 2020 - ingentaconnect.com
… the cachexia and sarcopenia due to increased catabolism. Pro-inflammatory cytokines induce
the … However, the precise molecular mechanism involved still remains elusive. TGF-β; an …

Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice

M Barns, C Gondro, RL Tellam… - The international journal …, 2014 - Elsevier
molecular mechanisms that are associated with the onset and progression of sarcopenia. A
… ; (4) no evidence for a role of inflammation in sarcopenia development nor pathology; (5) a …

[HTML][HTML] Mediators and patterns of muscle loss in chronic systemic inflammation

S Pérez-Baos, I Prieto-Potin, JA Roman-Blas… - Frontiers in …, 2018 - frontiersin.org
… of chronic inflammation-related sarcopenia has been … chronic inflammation and sarcopenia,
there are still substantial gaps, which may account for the lack of treatments for sarcopenia. …

[HTML][HTML] Sarcopenic obesity, insulin resistance, and their implications in cardiovascular and metabolic consequences

S Hong, KM Choi - International journal of molecular sciences, 2020 - mdpi.com
… on the molecular mechanisms linking sarcopenic obesity and … We also discuss the impact
and mechanism of sarcopenicInflammation due to sarcopenic obesity results in reduced NO, …

[HTML][HTML] Biochemical pathways of sarcopenia and their modulation by physical exercise: a narrative review

MM Ziaaldini, E Marzetti, A Picca, Z Murlasits - Frontiers in medicine, 2017 - frontiersin.org
… , the cellular and molecular mechanisms underlying such … the onset and progression of
sarcopenia. We subsequently … in immune system modulation, inflammation, cell survival, and …

Sarcopenia and the inflammatory cytokines

A Orzechowski - Sarcopenia, 2021 - Elsevier
… The basic molecular mechanism of inflammation is led by an intracellular signaling platform
known as inflammasome [16]. It is put together when cytosolic pattern recognition receptor, …

Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review

C Li, K Yu, N Shyh‐Chang, Z Jiang… - … , sarcopenia and …, 2022 - Wiley Online Library
… of a pathogenic mechanism with multiple drivers … inflammation to sarcopenia, suggesting
that a metabaging cycle that spreads systemically may be the root cause for obesity, sarcopenia

[HTML][HTML] Frailty and sarcopenia: the potential role of an aged immune system

D Wilson, T Jackson, E Sapey, JM Lord - Ageing research reviews, 2017 - Elsevier
… Therefore it is plausible that neutrophils play a key role in the inflammatory mechanisms
seen in sarcopenia and frailty. Neutrophils are central to tissue repair and research has …

[HTML][HTML] Nutrition and microRNAs: novel insights to fight sarcopenia

A Barbiera, L Pelosi, G Sica, BM Scicchitano - Antioxidants, 2020 - mdpi.com
… most relevant molecular mechanisms related to the pathophysiological effect of sarcopenia.
Besides… In muscle, pro-inflammatory cytokines such as TNF regulate sarcopenia through the …

The association between sarcopenia and diabetes: from pathophysiology mechanism to therapeutic strategy

H Chen, X Huang, M Dong, S Wen… - … Syndrome and Obesity, 2023 - Taylor & Francis
… main inflammatory molecules involved in inflammation are TNF-α, IL-6, IL-1 and chemokines,
which promote inflammatory … Citation84 The specific molecular mechanisms underlying the …