Apoptosis and caspases regulate death and inflammation in sepsis
RS Hotchkiss, DW Nicholson - Nature Reviews Immunology, 2006 - nature.com
… addition to active cell-death caspases, lymphocytes from patients with sepsis have many other
… caspase-3 inhibitor decreased sepsis-induced apoptosis and improved survival in sepsis …
… caspase-3 inhibitor decreased sepsis-induced apoptosis and improved survival in sepsis …
[HTML][HTML] Revisiting caspases in sepsis
… , and their striking roles in sepsis have been focused elaborately in a number … caspases in
terms of apoptosis, pyroptosis, necroptosis and inflammation and focused their links in sepsis …
terms of apoptosis, pyroptosis, necroptosis and inflammation and focused their links in sepsis …
[HTML][HTML] The inflammatory caspases: guardians against infections and sepsis
AM Scott, M Saleh - Cell Death & Differentiation, 2007 - nature.com
… cell death. Here, we review reports describing a role for caspase-1 in macrophage apoptosis
in response to infection by … , and a role for caspases-1 and -11 in neuronal apoptosis and …
in response to infection by … , and a role for caspases-1 and -11 in neuronal apoptosis and …
Apoptosis in sepsis
R Mahidhara, TR Billiar - Critical care medicine, 2000 - journals.lww.com
… has led to a reevaluation of the model of sepsis and dysregulated systemic inflammation. …
The second main committed apoptotic event is the activation of caspase 3 (23) . Caspase …
The second main committed apoptotic event is the activation of caspase 3 (23) . Caspase …
The inflammatory caspases: key players in the host response to pathogenic invasion and sepsis
A Nadiri, MK Wolinski, M Saleh - The Journal of Immunology, 2006 - journals.aai.org
… the inflammatory caspases play a direct role in apoptosis, as … both their execution of cell death
and their cellular “apoptotic” … the inflammatory caspases, their function in inflammation and …
and their cellular “apoptotic” … the inflammatory caspases, their function in inflammation and …
Lymphocyte apoptosis, caspase activation and inflammatory response in septic shock
G Delogu, G Famularo, G Tellan, M Marandola… - Infection, 2008 - Springer
… elevated blood levels of soluble caspase-1 in early septic shock represents in our opinion …
Caspase-1, the founding member of caspase family is predominantly involved in inflammation …
Caspase-1, the founding member of caspase family is predominantly involved in inflammation …
Cellular apoptosis and organ injury in sepsis: a review
C Power, N Fanning, HP Redmond - Shock, 2002 - journals.lww.com
… helps explain the absence of inflammation associated with apoptosis. … role of caspases as
effectors of apoptosis came from the fact that overexpression of caspases induced apoptosis ( …
effectors of apoptosis came from the fact that overexpression of caspases induced apoptosis ( …
[HTML][HTML] Simultaneous activation of apoptosis and inflammation in pathogenesis of septic shock: a hypothesis
VD Joshi, DV Kalvakolanu, AS Cross - FEBS letters, 2003 - Elsevier
… caspase inhibition and the importance of apoptosis and inflammation in different models of
sepsis, we hypothesize that simultaneous activation of apoptotic cell death and inflammation …
sepsis, we hypothesize that simultaneous activation of apoptotic cell death and inflammation …
[HTML][HTML] Inflammatory caspases: key regulators of inflammation and cell death
DJ Fernández, M Lamkanfi - Biological chemistry, 2015 - degruyter.com
… Infection and … inflammatory responses by interfering with caspase-1 activation and other
innate immune pathways. Here, we recapitulate the reported roles of inflammatory caspases …
innate immune pathways. Here, we recapitulate the reported roles of inflammatory caspases …
Advances in understanding sepsis
M Shimaoka, EJ Park - European Journal of Anaesthesiology, 2008 - cambridge.org
… Summary Sepsis, a systemic inflammatory response to infection, … sepsis-induced lymphocyte
apoptosis and reduced lethality [42]. Caspase inhibitors have been used to block apoptosis …
apoptosis and reduced lethality [42]. Caspase inhibitors have been used to block apoptosis …
相关搜索
- lymphocyte apoptosis caspase activation
- inflammatory caspases innate immunity
- inflammatory caspases infections and sepsis
- apoptotic cell death in sepsis
- apoptosis in sepsis therapeutic exploration
- inflammatory caspases key regulators of inflammation
- inflammatory caspases great balls of fire
- simultaneous activation apoptosis and inflammation
- inflammatory caspases pathogenic invasion
- apoptosis in sepsis role and regulation
- apoptosis in sepsis potential therapeutic targets
- inflammatory caspases unified model
- caspase activation pathways apoptosis and immunity
- role of caspase 8 inflammatory signalling
- sepsis and shock leukocyte apoptosis
- caspase 1 multifunctional inflammatory mediator