Molecular pathways: the complex roles of inflammation pathways in the development and treatment of liver cancer

K Nikolaou, M Sarris, I Talianidis - Clinical Cancer Research, 2013 - AACR
… a paradigm for inflammation-induced cancer, … inflammation and carcinogenesis are triggered
by a complex cross-talk between NF-κB, c-jun-NH 2 -kinase, and STAT3 signaling pathways

The complex role of estrogens in inflammation

RH Straub - Endocrine reviews, 2007 - academic.oup.com
… to the immunomodulating role of estrogens. On one side, we recognize inhibition of bone
resorption and suppression of inflammation in several animal models of chronic inflammatory

The nuclear factor NF-κB pathway in inflammation

T Lawrence - Cold Spring Harbor perspectives in biology, 2009 - cshperspectives.cshlp.org
complex roles for the NF-κB in inflammation that suggest both pro- and anti-inflammatory roles
for this pathway. … mice has revealed complex roles for the NF-κB pathway in inflammation. …

[HTML][HTML] The crucial roles of inflammatory mediators in inflammation: A review

LA Abdulkhaleq, MA Assi, R Abdullah… - Veterinary …, 2018 - ncbi.nlm.nih.gov
… This complex response involves leukocytes cells such as macrophages, neutrophils, and …
the role of the inflammatory cells as well as their by-products in the mediation of inflammatory

Origin and physiological roles of inflammation

R Medzhitov - Nature, 2008 - nature.com
… of each component for several inflammatory pathways. b, Inducers of inflammation can be
classified as … Inflammation is exceedingly complex and equally fascinating. It has a crucial …

NF-κB: a key role in inflammatory diseases

PP Tak, GS Firestein - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
complexes, plays a central role in inflammation through its ability to induce transcription of
proinflammatory genes (1). This pathway … -κB proteins, their role in inflammatory disease, the …

The resolution of inflammation: anti-inflammatory roles for NF-κB

T Lawrence, C Fong - The international journal of biochemistry & cell …, 2010 - Elsevier
pathway in the treatment of inflammatory diseases. In this review we will discuss the emerging
role of NF-κB in the resolution of inflammation … The inflammatory response is a complex

New regulators of NF-κB in inflammation

S Ghosh, MS Hayden - Nature Reviews Immunology, 2008 - nature.com
… an inflammatory milieu. In fact, NF-κB has a fundamental role in mediating all of the classical
attributes of inflammation — … that IκB proteins could have complex roles in NF-κB regulation. …

The complex network between inflammation and colorectal cancer: A systematic review of the literature

R Percario, P Panaccio, FF di Mola, T Grottola… - Cancers, 2021 - mdpi.com
role of inflammation in the tumorigenesis of colorectal cancer through different pathways:
this may have a diagnostic and clinical role … carcinogenesis by treating inflammation. In vitro …

Nuclear factor kappa B signaling complexes in acute inflammation

S Rius-Pérez, S Pérez, P Martí-Andrés… - Antioxidants & redox …, 2020 - liebertpub.com
… CBP/p300 playing opposite roles in the regulation of inflammatory genes. S-nitrosylation
or … complexes to regulate selectively the expression of target genes in acute inflammation. …