Molecular pathways: the complex roles of inflammation pathways in the development and treatment of liver cancer

K Nikolaou, M Sarris, I Talianidis - Clinical Cancer Research, 2013 - AACR
… Molecular dissection of the mechanisms involved in the interplay between these pathways
… initiated by chronic liver inflammation and culminating in liver cancer. Clin Cancer Res; 19(…

Inflammation and liver cancer: new molecular links

C Berasain, J Castillo, MJ Perugorria… - Annals of the New …, 2009 - Wiley Online Library
… and their signaling systems in liver cirrhosis and HCC, the critical components linking
inflammation and liver cancer are only beginning to be exposed. These pathways are depicted in …

The inflammation and liver cancer

A Bishayee - Inflammation and cancer, 2014 - Springer
… associated with the inhibition of inflammatory signaling as well as … of anti-inflammatory
agents to prevent and treat liver cancer are … inflammatory pathways implicated in liver cancer is …

[HTML][HTML] Inflammation and liver cancer: molecular mechanisms and therapeutic targets

YM Yang, SY Kim, E Seki - Seminars in liver disease, 2019 - thieme-connect.com
… these pathways could be therapeutic targets. The authors will also discuss cholangiocarcinoma
and liver metastasis because biliary inflammation and tumor-… tumor-derived inflammatory

[PDF][PDF] Understanding the inflammation-cancer transformation in the development of primary liver cancer

HJ Chen, MH Hu, FG Xu, HJ Xu, JJ She, HP Xia - Hepatoma Res, 2018 - academia.edu
… , inflammation cytokines and hepatocarcinogenic pathways related to the … liver cancer. So
it is an interesting strategy to further investigate the antiinflammatory treatment for liver cancer. …

[HTML][HTML] Obesity, inflammation, and liver cancer

B Sun, M Karin - Journal of hepatology, 2012 - Elsevier
… The latter is a known liver cancer risk factor. In fact due to its … contributor to overall
hepatocellular carcinoma burden than … pathways associated with obesity and liver inflammation

[HTML][HTML] NF-κB and STAT3–key players in liver inflammation and cancer

G He, M Karin - Cell research, 2011 - nature.com
… This review will focus on recent studies on the roles of NF-κB and STAT3 in liver cancer.
Interactions between the two pathways and their potential as therapeutic targets will also be …

The epidermal growth factor receptor: a link between inflammation and liver cancer

C Berasain, MJ Perugorria, MU Latasa… - Experimental …, 2009 - journals.sagepub.com
… believed to cause liver tumors also via indirect pathways (4–7). These pathways involve the
accumulation … proliferation elicited by parenchymal cell loss and chronic inflammation (8, 9). …

[HTML][HTML] Role of microRNAs in inflammation-associated liver cancer

L Huan, LH Liang, XH He - Cancer biology & medicine, 2016 - ncbi.nlm.nih.gov
… Another well-known signaling pathway that links inflammation and cancer is the Janus …
This signaling pathway is also constitutively activated in most cancers. STAT3, one of the most …

[HTML][HTML] … extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/inflammation pathway

AA Hamza, GH Heeba, S Hamza, A Abdalla… - Biomedicine & …, 2021 - Elsevier
… -AAF-treated rats for TUNEL, M30 and caspase-3 liver tissues. … -preventative impact on liver
cancer by inhibiting the growth … inflammatory damage, ginger protects rat liver against cancer