Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history

CW Lees, J Satsangi - Expert review of gastroenterology & …, 2009 - Taylor & Francis
… in 200 people in western Europe and Northern America develop a form of chronic inflammatory
bowel disease (IBD), with disruption of intestinal homeostasis and subsequent chronic …

[HTML][HTML] Role of cytokines in inflammatory bowel disease

F Sanchez-Muñoz, A Dominguez-Lopez… - World journal of …, 2008 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), which includes Crohn’s disease (CD) and ulcerative
colitis (UC), represents a group of chronic disorders characterized by inflammation of the …

[HTML][HTML] Immunological pathogenesis of inflammatory bowel disease

SH Lee, J eun Kwon, ML Cho - Intestinal research, 2018 - synapse.koreamed.org
… It is well documented that Th17 inhibition can decrease the development of acute colitis by
reducing inflammation.4 Additionally, innate lymphoid cells (ILCs) were recently discovered …

Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics

NT Ventham, NA Kennedy, ER Nimmo, J Satsangi - Gastroenterology, 2013 - Elsevier
… profile after the disease process has been established, rather than describing a temporal
relationship between an epigenetic alteration and subsequent disease development. The …

Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
… For example, germ-free mice do not develop colitis, and inflammatory changes can be induced
… to colitis development, antibiotic administration early in life increased the risk of colitis [7]. …

[HTML][HTML] Advances in the development of new biologics in inflammatory bowel disease

B Ungar, U Kopylov - … : quarterly publication of the Hellenic Society …, 2016 - ncbi.nlm.nih.gov
… the field of inflammatory bowel disease (IBD) therapy has been related to development of
anti-… pathogenesis of the inflammatory process in IBD, have led to the development of several …

Environmental factors and risk of developing paediatric inflammatory bowel disease—a population based study 2007–2009

C Jakobsen, A Paerregaard… - … of Crohn's and Colitis, 2013 - academic.oup.com
… for developing inflammatory bowel disease (IBD) in children < 15 years of age. … and
inflammatory bowel disease No association between degree of urbanisation and risk of developing

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

MZ Cader, A Kaser - Gut, 2013 - gut.bmj.com
… These studies have also revealed how proper development and function of the intestinal …
may lead to inflammatory bowel disease (IBD). We highlight the latest developments within this …

[HTML][HTML] Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models

E Mizoguchi, D Low, Y Ezaki, T Okada - Intestinal research, 2020 - synapse.koreamed.org
… pathogenesis underlining inflammatory bowel disease (IBD) is … of IBD, Crohn’s disease
(CD) and ulcerative colitis (UC), and … disease development and also to ameliorate established …

Inflammatory bowel disease in early childhood and adolescence: special considerations

P Mamula, JE Markowitz… - Gastroenterology …, 2003 - gastro.theclinics.com
… adult and pediatric patients diagnosed with inflammatory bowel disease (IBD) are obvious
… have a potential to enable us to develop better understanding of IBD etiology, especially …