Inflammatory bowel disease (IBD) is idiopathic, lifelong, immune-mediated diseases, for
which curative therapies are not yet available. In the last 15 years, the introduction of …

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …

… inflammatory bowel disease (IBD). Encompassing a spectrum of diseases characterized by
chronic GI inflammation, … role of the microbiota in disease development it is important to first …

… Inflammatory bowel disease manifests during childhood or adolescence in 20% to 25% of …
in pubertal development as a complication of the inflammatory process in Crohn's disease (CD…

… in the IL-10R gene will develop spontaneous colitis with 100% penetrance, in vivo studies …
commensal bacteria that act as triggers—in the development of colitis (67). Thus, it is possible …

Background Use of antibiotics in early life has been linked with childhood inflammatory bowel
disease (IBD), but data for adults are mixed, and based on smaller investigations that did …

… The first signs of these chronic diseases often develop at an early age; early recognition,
good management, and continuity of care may. have important consequences for the quality of …

… our own group in inflammatorybowel disease colonic mucosal … cancer development in
inflammatory bowel disease mucosa [… malignant change in inflammatory bowel disease. A similar …

… to developing a severe, spontaneous intestinal inflammation when … intestinal inflammation
seen in mdr1a −/− mice has a pathology similar to that of human inflammatory bowel disease (…

… Key interactions involved in susceptibility to development of inflammatory bowel diseases. …
can carry key risk genes, without developing the diseases, lends strong support to the …