… of the microbiota can result in pathologic inflammatory processes such as inflammatory
bowel disease (IBD), which primarily consists of ulcerative colitis (UC) and Crohn's disease (CD). …

… were valid measures of the effects of inflammatory bowel disease on health, we would expect
… health, vitality, and pain—the areas of health most affected by inflammatory bowel disease. …

… plays an important role in modulating disease development. Genetic factors also differ between
… , may lead to the discovery of critical etiologic factors that lead to the development of IBD. …

… ’s disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel disease
(… The development of IBD in infancy is extremely rare. Published data from epidemiological …

… Studies have shown that obesity impacts disease development and response to therapy
in patients with IBD and other autoimmune conditions. The observation that adipose tissue …

… factors may tip the balance between homeostasis and intestinal inflammation, presenting
future challenges for the development of new therapies for inflammatory bowel disease. …

… and deep ulcers that precede the development of a stricture. A … fistula can develop within the
most severe inflammatory area. … disease progression, from aphtous ulcers to development of …

… factors play a significant role in determining inflammatory bowel disease (IBD) susceptibility.
… : mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. …

… Patients with ileal resections and a diverting ileostomy excluding the neoterminal ileum
fail to develop recurrent disease until reanastomosis is performed. Furthermore, infusion of …

… As can be seen in Box 2, a large number of mice with different genetic defects develop
spontaneous mucosal inflammation. So, the first principle is that entirely different genetic …