Induced and natural regulatory T cells in the development of inflammatory bowel disease

CG Mayne, CB Williams - Inflammatory bowel diseases, 2013 - academic.oup.com
… of the microbiota can result in pathologic inflammatory processes such as inflammatory
bowel disease (IBD), which primarily consists of ulcerative colitis (UC) and Crohn's disease (CD). …

The UK IBDQ—a British version of the inflammatory bowel disease questionnaire: development and validation

W Cheung, AM Garratt, IT Russell… - Journal of clinical …, 2000 - Elsevier
… were valid measures of the effects of inflammatory bowel disease on health, we would expect
… health, vitality, and pain—the areas of health most affected by inflammatory bowel disease. …

Emerging leadership lecture: Inflammatory bowel disease in A sia: Emergence of a “W estern” disease

SC Ng - Journal of gastroenterology and hepatology, 2015 - Wiley Online Library
… plays an important role in modulating disease development. Genetic factors also differ between
… , may lead to the discovery of critical etiologic factors that lead to the development of IBD. …

Does inflammatory bowel disease develop in infants?

MD Kappelman, RJ Grand - Inflammatory bowel diseases, 2008 - academic.oup.com
… ’s disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel disease
(… The development of IBD in infancy is extremely rare. Published data from epidemiological …

[HTML][HTML] Interaction of obesity and inflammatory bowel disease

JW Harper, TL Zisman - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
… Studies have shown that obesity impacts disease development and response to therapy
in patients with IBD and other autoimmune conditions. The observation that adipose tissue …

Intestinal homeostasis and its breakdown in inflammatory bowel disease

KJ Maloy, F Powrie - Nature, 2011 - nature.com
… factors may tip the balance between homeostasis and intestinal inflammation, presenting
future challenges for the development of new therapies for inflammatory bowel disease. …

Epidemiology and natural history of inflammatory bowel diseases

J Cosnes, C Gower–Rousseau, P Seksik, A Cortot - Gastroenterology, 2011 - Elsevier
… and deep ulcers that precede the development of a stricture. A … fistula can develop within the
most severe inflammatory area. … disease progression, from aphtous ulcers to development of …

The genetics of inflammatory bowel disease

DK Bonen, JH Cho - Gastroenterology, 2003 - Elsevier
… factors play a significant role in determining inflammatory bowel disease (IBD) susceptibility.
… : mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. …

Inflammatory bowel disease: etiology and pathogenesis

C Fiocchi - Gastroenterology, 1998 - Elsevier
… Patients with ileal resections and a diverting ileostomy excluding the neoterminal ileum
fail to develop recurrent disease until reanastomosis is performed. Furthermore, infusion of …

The immunological and genetic basis of inflammatory bowel disease

G Bouma, W Strober - Nature reviews immunology, 2003 - nature.com
… As can be seen in Box 2, a large number of mice with different genetic defects develop
spontaneous mucosal inflammation. So, the first principle is that entirely different genetic …