[HTML][HTML] Vedolizumab in the treatment of inflammatory bowel disease: evolving paradigms

B Crooks, T Barnes, JK Limdi - Drugs in Context, 2020 - ncbi.nlm.nih.gov
Vedolizumab is the first licensed drug in a group of ‘gut-selective’ biological agents used to
treat inflammatory bowel diseases… established the efficacy of vedolizumab for the induction …

Biologic therapy of inflammatory bowel disease

WJ Sandborn, SR Targan - Gastroenterology, 2002 - Elsevier
… Many biologic therapies are being evaluated for the treatment of the chronic inflammatory
bowel diseases, Crohn's disease and ulcerative colitis. Biologic compounds proven to be …

Risk of postoperative complications among inflammatory bowel disease patients treated preoperatively with vedolizumab

A Yamada, Y Komaki, N Patel, F Komaki… - Official journal of the …, 2017 - journals.lww.com
… cells play pivotal roles in the pathogenesis of inflammatory bowel disease (IBD) ( 1 , 2 ). …
from the systemic circulation to inflamed tissues ( 3 , 4 , 5 , 6 ). Vedolizumab, a novel humanized …

Safety and efficacy of combination treatment with calcineurin inhibitors and vedolizumab in patients with refractory inflammatory bowel disease

B Christensen, PR Gibson, D Micic, RJ Colman… - Clinical …, 2019 - Elsevier
… a bridge to maintenance vedolizumab treatment when applied to vedolizumab initiation or
… nonresponse to vedolizumab. On long-term follow-up evaluation, vedolizumab was able to …

Biological therapies for inflammatory bowel diseases

P Rutgeerts, S Vermeire, G Van Assche - Gastroenterology, 2009 - Elsevier
Crohn's disease and ulcerative colitis are chronic disabling inflammatory bowel diseases
(IBDs). Although the causes of IBD are unknown, defects in innate and adaptive immune …

Vedolizumab is effective and safe in real-life treatment of inflammatory bowel diseases outpatients: a multicenter, observational study in primary inflammatory bowel …

A Tursi, G Mocci, R Faggiani, L Allegretta… - European journal of …, 2019 - Elsevier
… in managing ulcerative colitis (UC) and Crohn's disease (CD) patients with vedolizumab (VDZ)
are … in inflammatory bowel diseases (IBD) outpatients in primary gastroenterology centers. …

Efficacy and safety of vedolizumab for induction of remission in inflammatory bowel disease—the Israeli real-world experience

U Kopylov, Y Ron, I Avni-Biron… - Inflammatory bowel …, 2017 - academic.oup.com
Vedolizumab (VDZ) is a monoclonal antibody which blocks … remission in both ulcerative colitis
(UC) and Crohn's disease (CD). … in treating patients with inflammatory bowel disease (IBD) …

[HTML][HTML] A real-world, long-term experience on effectiveness and safety of vedolizumab in adult patients with inflammatory bowel disease: The Cross Pennine study

MV Lenti, S Levison, E Eliadou, R Willert… - … and Liver Disease, 2018 - Elsevier
… Real-life data on vedolizumab effectiveness in inflammatory bowel disease (IBD) are still
emerging. Data on the comparative safety of the gut selective profile are of particular interest. …

Postoperative outcomes in vedolizumab-treated patients undergoing abdominal operations for inflammatory bowel disease

AL Lightner, LE Raffals, KL Mathis… - … Crohn's and Colitis, 2017 - academic.oup.com
… , vedolizumab is an effective treatment for moderate to severe CD and UC, offering an attractive
alternative to anti-TNFα therapy… surgery will be receiving vedolizumab therapy. We found …

The safety of vedolizumab for ulcerative colitis and Crohn's disease

JF Colombel, BE Sands, P Rutgeerts, W Sandborn… - Gut, 2017 - gut.bmj.com
… Nevertheless, important questions remain about the long-term safety (LTS) of vedolizumab
in patients with inflammatory bowel disease (IBD). To address this issue, the cumulative LTS …