Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
… of inflammation, the crosstalk between tumor development and inflammatory processes.
We also highlight potential targets for harnessing inflammation in the treatment of cancer. …

Signaling pathways in inflammation and anti-inflammatory therapies

YT Yeung, F Aziz, A Guerrero-Castilla… - Current …, 2018 - ingentaconnect.com
… Given the importance of these signaling pathways in chronic inflammatory diseases, in this
… in inflammation and current therapeutic strategies in order to encounter abnormal signaling. …

Signaling pathways associated with inflammatory bowel disease

J Wei, J Feng - Recent patents on inflammation & allergy drug …, 2010 - ingentaconnect.com
… This review will focus on the signaling pathways associated with IBDs. We will discuss the
signaling pathways that are associated with mutational genes, inflammatory process, and …

[HTML][HTML] Nrf2 signaling pathway: Pivotal roles in inflammation

SMU Ahmed, L Luo, A Namani, XJ Wang… - Biochimica et Biophysica …, 2017 - Elsevier
… Therefore, the identification of new Nrf2-dependent anti-inflammatory … /Nrf2/ARE signal
pathway and its downstream genes, the effects of this pathway on animal models of inflammatory

NF-κB signaling pathway, inflammation and colorectal cancer

S Wang, Z Liu, L Wang, X Zhang - Cellular & molecular immunology, 2009 - nature.com
… It has been proposed that noxious compounds released during chronic inflammation damage
DNA and/or alter cell survival, results in carcinogenesis of CRC (56). NSAIDs have been …

An overview of Nrf2 signaling pathway and its role in inflammation

S Saha, B Buttari, E Panieri, E Profumo, L Saso - Molecules, 2020 - mdpi.com
… of Nrf2 signaling pathway in inflammation, therefore, it is also worthwhile to discuss natural
antioxidants which could modulate Nrf2-dependent treatment of inflammatory diseases [241]. …

The essential roles of Toll-like receptor signaling pathways in sterile inflammatory diseases

Q Lin, M Li, D Fang, J Fang, SB Su - International immunopharmacology, 2011 - Elsevier
… contribute to the development of sterile inflammatory diseases, such as rheumatoid …
inflammatory and immune diseases [5]. Since many aspects of TLR biology and signaling pathways

[HTML][HTML] The anti-inflammatory and anti-oxidant mechanisms of the Keap1/Nrf2/ARE signaling pathway in chronic diseases

W Tu, H Wang, S Li, Q Liu, H Sha - Aging and disease, 2019 - ncbi.nlm.nih.gov
pathway and its anti-inflammatory and anti-oxidant effects, we hypothesize that the anti-inflammatory
/Nrf2/ARE signaling pathway. Hence, this would be the focus of our future research. …

[PDF][PDF] The TSC-mTOR signaling pathway regulates the innate inflammatory response

T Weichhart, G Costantino, M Poglitsch, M Rosner… - Immunity, 2008 - cell.com
… To directly address whether the mTOR pathway controls inflammatory cytokine production,
we made use of murine embryonic fibroblasts (MEFs) lacking TSC2, a key negative regulator …

[HTML][HTML] Inflammation-and stress-related signaling pathways in hepatocarcinogenesis

H Nakagawa, S Maeda - World journal of gastroenterology: WJG, 2012 - ncbi.nlm.nih.gov
… As discussed in this review, recent studies have indicated that NF-κB, STAT3, and stress-activated
MAPK signaling pathways play key roles in inflammation-mediated …