TNF-α signalling and inflammation: interactions between old acquaintances
H Zelová, J Hošek - Inflammation research, 2013 - Springer
… On the other side, an inadequate inflammatory reaction can result in tissue damage and
in severe cases it could even cause organ failure and death [68]. Optimally, the …
in severe cases it could even cause organ failure and death [68]. Optimally, the …
Regulation of inflammatory vascular damage
AB Lentsch, PA Ward - The Journal of pathology, 2000 - Wiley Online Library
… In organs such as the lung, a number of stimuli may result in activation of residential
macrophage populations which respond by producing pro-inflammatory mediators such as TNFα …
macrophage populations which respond by producing pro-inflammatory mediators such as TNFα …
… adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6
GW Roddy, JY Oh, RH Lee, TJ Bartosh, J Ylostalo… - Stem …, 2011 - academic.oup.com
… corneal opacity and inflammation without engraftment after … the multipotent anti-inflammatory
protein TNF-α stimulated gene/… administered hMSCs reduce inflammatory damage to the …
protein TNF-α stimulated gene/… administered hMSCs reduce inflammatory damage to the …
Pro-inflammatory cytokine TNF-alpha as a neuroprotective agent in the brain
I Figiel - Acta neurobiologiae experimentalis, 2008 - ane.pl
… In this study, mice deficient in TNF-α receptors showed exacerbated neuronal damage after
… microglial activation and neuronal damage. The differences in the TNF-α signaling, including …
… microglial activation and neuronal damage. The differences in the TNF-α signaling, including …
[HTML][HTML] Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes
… While multiple inflammatory cytokines are produced by innate immune cells during SARS-…
of TNF-α and IFN-γ induced inflammatory cell death characterized by inflammatory cell death, …
of TNF-α and IFN-γ induced inflammatory cell death characterized by inflammatory cell death, …
[HTML][HTML] Relevance of TNF-α in the context of other inflammatory cytokines in the progression of diabetic nephropathy
L Sun, YS Kanwar - Kidney international, 2015 - Elsevier
… The most important inflammatory cytokines that are induced in this setting include TNF-α, IL-1…
influx and cytokine-induced inflammatory damage in the setting of hyperglycemia is derived …
influx and cytokine-induced inflammatory damage in the setting of hyperglycemia is derived …
Differential inflammatory responses in aging and disease: TNF-α and IL-6 as possible biomarkers
…, JJ Solano, A Coto-Montes - Free Radical Biology …, 2010 - Elsevier
… Commensurate with this fact, we found significantly more protein damage in older … of
proteolytic systems that normally destroy damaged proteins. Proteolytic system alterations are also …
proteolytic systems that normally destroy damaged proteins. Proteolytic system alterations are also …
[HTML][HTML] Immunoregulatory role of TNFα in inflammatory kidney diseases
T Ernandez, T Mayadas - Kidney international, 2009 - Elsevier
… , 4 , 5 TNFα is now more recognized for its role in inflammatory and autoimmune diseases
such as … TNFα is largely implicated in renal inflammation and glomerular damage induced by …
such as … TNFα is largely implicated in renal inflammation and glomerular damage induced by …
Changes of inflammatory cytokines and neurotrophins emphasized their roles in hypoxic–ischemic brain damage
Y Wang, M Cao, A Liu, W Di, F Zhao… - International Journal of …, 2013 - Taylor & Francis
… Our results showed that the increased expression of inflammatory factors TNF-α, ICAM-1, …
expression of inflammatory factors and neurotrophins on the outcome of brain damage. Further …
expression of inflammatory factors and neurotrophins on the outcome of brain damage. Further …
[HTML][HTML] Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes
J Kim, M Xu, R Xo, A Mates, GL Wilson… - Osteoarthritis and …, 2010 - Elsevier
… The principal findings of the present work are that: (1) the pro-inflammatory cytokines IL-1β
and TNF-α disturb normal mitochondrial function in both normal and OA human chondrocytes …
and TNF-α disturb normal mitochondrial function in both normal and OA human chondrocytes …
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