IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases

X Song, Y Qian - Cellular signalling, 2013 - Elsevier
… signalings of this family cytokines and their impacts on the inflammatory responses or disorders.
… of this family cytokines and their impacts on the pathogenesis of inflammatory diseases. …

Cytokines in inflammatory disease

S Kany, JT Vollrath, B Relja - International journal of molecular sciences, 2019 - mdpi.com
… of a broad variety of inflammatory cytokines. Numerous studies have implicated that
inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the …

IL-1 family cytokines trigger sterile inflammatory disease

JR Lukens, JM Gross, TD Kanneganti - Frontiers in immunology, 2012 - frontiersin.org
… -1 family cytokines play in sterile inflammatory diseases. … diseases (Figure 1). In this review
we focus on the pivotal role of IL-1 family cytokines in various sterile inflammatory diseases. …

[PDF][PDF] The IL-1 family and inflammatory diseases

CA Dinarello - Clinical and experimental rheumatology, 2002 - clinexprheumatol.org
… The IL-1agonist family, IL-1α, IL-1β and IL-1, are unique in the cytokine families. Each is
initially synthesized as precursor molecules without a signal peptide. After processing by the re…

[PDF][PDF] Cytokines and their role in health and disease: a brief overview

K Gulati, S Guhathakurta, J Joshi, N Rai, A Ray - Moj Immunol, 2016 - researchgate.net
… Role of cytokines in diseases Bronchial asthma: Bronchial asthma is an inflammatory
disease of the airways and is associated with bronchial hyper reactivity and reversible airway …

Interleukin-1 family cytokines: keystones in liver inflammatory diseases

L Barbier, M Ferhat, E Salamé, A Robin… - Frontiers in …, 2019 - frontiersin.org
… in several inflammatory diseases such as obesity, atherosclerosis, cancer, viral and
parasite infections, and auto-inflammatory syndromes as well as liver diseases. Inflammation

The IL-1 family cytokines and receptors in autoimmune diseases

P Migliorini, P Italiani, F Pratesi, I Puxeddu… - Autoimmunity …, 2020 - Elsevier
… IL-1 family cytokines in autoimmune and chronic inflammatory and degenerative diseases,
with … on the involvement of IL-1 cytokines in the pathogenesis vs. the clinical features of these …

Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer

SA Jones, BJ Jenkins - Nature reviews immunology, 2018 - nature.com
… of these cytokine activities often promotes chronic disease and … roles for IL-6 family members
in infection, chronic inflammation, … designed to manipulate these cytokines in disease. …

IL-17 family: cytokines, receptors and signaling

C Gu, L Wu, X Li - Cytokine, 2013 - Elsevier
… The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A–F, plays crucial
… development of inflammatory diseases. Although IL-17A is the signature cytokine produced …

IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets

N Unver, F McAllister - Cytokine & growth factor reviews, 2018 - Elsevier
… IL-6 is a critical cytokine in acute phase response and involved in the pathogenesis of …
inflammatory diseases including cancer. Studies have highlighted that levels of IL-6 and its family