Inflammatory mechanisms in ischemic stroke: therapeutic approaches

SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
… The increase in oxygen free radicals triggers the expression of a number of pro-inflammatory
genes by inducing the synthesis of transcription factors, including NF-κB, hypoxia inducible …

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

R Jin, G Yang, G Li - Journal of leukocyte biology, 2010 - academic.oup.com
… different inflammatory cells following focal cerebral I/R. We discuss how these cells contribute
to ischemic … questions about inflammatory cells in the pathophysiology of ischemic stroke. …

Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke

JC Bis, SR Heckbert, NL Smith, AP Reiner, K Rice… - Atherosclerosis, 2008 - Elsevier
… study of common genetic variation among eight inflammation-related genes, one gene (IL-…
We investigated gene variation among eight inflammation-related genes by analyzing 38 …

Inflammatory cytokines in acute ischemic stroke

A Tuttolomondo, D Di Raimondo… - Current …, 2008 - ingentaconnect.com
… , welldesigned studies will provide the currently lacking information and will gradually
improve our knowledge in the field of genetic polymorphisms in acute ischemic stroke practice. …

Proinflammatory genetic profiles in subjects with history of ischemic stroke

A Flex, E Gaetani, P Papaleo, G Straface, AS Proia… - Stroke, 2004 - Am Heart Assoc
… the effect of genes in linkage disequilibrium with the genes … of genes encoding for prototypical
inflammatory molecules, such … history of ischemic stroke. Synergistic effects between these …

Inflammation and infections as risk factors for ischemic stroke

PJ Lindsberg, AJ Grau - Stroke, 2003 - Am Heart Assoc
… It is one of our general hypotheses that infection/inflammation, specific genetic predispositions,
and traditional risk factors interact with each other and may cooperatively enhance the …

Update on inflammatory biomarkers and treatments in ischemic stroke

A Bonaventura, L Liberale, A Vecchié… - International journal of …, 2016 - mdpi.com
After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly induce
both beneficial and detrimental effects. In this narrative review, we updated evidence on …

Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

N Zhao, X Liu, Y Wang, X Liu, J Li, L Yu, L Ma… - Journal of …, 2012 - Springer
… Our results indicate that inflammatory genetic variants are associated with increased risk
of ischemic stroke in a Chinese Han population, particularly in non-hypertensive individuals. …

Inflammation in ischemic stroke subtypes

A Tuttolomondo, D Di Raimondo… - Current …, 2012 - ingentaconnect.com
… the currently lacking information and will gradually improve our knowledge in the field of
genetic polymorphisms in acute ischemic stroke practice At extracranial arterial territories, …

Inflammatory responses after ischemic stroke

JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
… Efferocytosis genes are upregulated in brain macrophages at day 5 post-pMCAO and
efferocytosis is dependent on STAT6 and Arg1 [106, 107]. Overexpression of Triggering Receptor …