Development of a behavioral model of TMJ pain in rats: the TMJ formalin test

RC Roveroni, CA Parada, M Cecılia, FA Veiga… - Pain, 2001 - Elsevier
formalin is a noxious stimulus widely used in animal behavioral experiments for studying
pain … a behavioral model to study the TMJ pain conditions by characterizing the nociceptive …

Synergism between fentanyl and tramadol in tonic inflammatory pain: the orofacial formalin test

HF Miranda, V Noriega, RJ Zepeda, F Sierralta… - Inflammation, 2012 - Springer
… The typical time course of the response to formalin is biphasic, … after formalin injection and
represents a tonic acute pain due to … after formalin injection and represents inflammatory pain. …

Analgesic properties of oleoylethanolamide (OEA) in visceral and inflammatory pain

M Suardíaz, G Estivill-Torrús, C Goicoechea, A Bilbao… - Pain, 2007 - journals.lww.com
… In order to evaluate the underlying mechanisms in the antinociceptive effect of OEA in
inflammatory pain, we investigated its effects on the formalin-evoked nociceptive behaviour in WT …

[HTML][HTML] Antinociceptive local activity of 4-allyl-1-hydroxy-2-methoxybenzene (eugenol) by the formalin test: an anti-inflammatory effect

DE Lugo-Lugo, AJ Pozos-Guillén… - Brazilian Journal of …, 2019 - SciELO Brasil
… naproxen diminished inflammatory pain by 41.6%, which is even less than our finding in
the formalin test during phases 1 and 2 (72.2 and 70%, respectively; p ≤0.05 vs. formalin 5%; …

Enhanced formalin nociceptive responses following L5 nerve ligation in the rat reveals neuropathy-induced inflammatory hyperalgesia

CJ LaBuda, R Donahue, PN Fuchs - Pain, 2001 - journals.lww.com
… to model neuropathic pain and the formalin test to model inflammatory pain, the purpose of
the present experiment was to determine if an increase in inflammatory responses developed …

Evidence for antinociceptive effects of combined administration of vitamin E and celecoxib in tail-flick and formalin test in male rats

MS Meymandi, G Sepehri, G Izadi, Z Zamiri - Pharmacological Reports, 2019 - Elsevier
… as well as antinociceptive and anti-inflammatory properties, so this study … pain assessment;
including tail-flick test, as the response to thermal pain, and formalin test as inflammatory pain

Formalin injection produces long-lasting hypersensitivity with characteristics of neuropathic pain

AB Salinas-Abarca, SH Avila-Rojas… - European journal of …, 2017 - Elsevier
… The formalin test is a widely used model of inflammatory pain. This model has been used in
mice, rats and dogs (Rodríguez and Pardo, 1968; Dubuisson and Dennis, 1977; Hunskaar et …

Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain

LH Guo, K Trautmann, HJ Schluesener - Journal of neuroimmunology, 2005 - Elsevier
… Furthermore, formalin-induced region-specific increase in activated … P2X 4 R is expressed
by microglia in the inflammatory pain. … cord dorsal horn in formalin-induced inflammatory pain. …

Interactions of inflammatory pain and morphine in infant rats: long-term behavioral effects

AT Bhutta, C Rovnaghi, PM Simpson, JM Gossett… - Physiology & …, 2001 - Elsevier
… Both neonatal morphine treatment and neonatal inflammatory paininflammatory pain
exhibited less locomotor activity than untreated controls. We conclude that neonatal formalin and …

Analgesic effects of Danggui-Shaoyao-San on various “phenotypes” of nociception and inflammation in a formalin pain model

JB Yin, KC Zhou, HH Wu, W Hu, T Ding, T Zhang… - Molecular …, 2016 - Springer
… in the formalin pain model via an amelioration of peripheral tissue injury and/or inflammation
Since monoamine neuromodulators, especially 5-HT, participates in descending pain