Peripheral morphine analgesia
C Stein, A Yassouridis - Pain, 1997 - journals.lww.com
… interesting for the treatment of chronic inflammatory pain. … the analgesic efficacy of intraarticular
morphine. This should promote the recognition of peripherally mediated opioid analgesia …
morphine. This should promote the recognition of peripherally mediated opioid analgesia …
Effect of peripheral morphine in a human model of acute inflammatory pain
J Lillesø, NA Hammer, JL Pedersen… - British journal of …, 2000 - academic.oup.com
… morphine had no acute antinociceptive effects in this human model of acute inflammatory
pain… Further, we were not able to detect any analgesic action of the low dose of morphine (2 mg…
pain… Further, we were not able to detect any analgesic action of the low dose of morphine (2 mg…
Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions
DJ Mayer, J Mao, J Holt… - Proceedings of the …, 1999 - National Acad Sciences
… inflammatory pain as well as opioid tolerance has significantly advanced our knowledge about
pain and pain … of neuropathic pain syndromes and result in reduced morphine analgesia …
pain and pain … of neuropathic pain syndromes and result in reduced morphine analgesia …
Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain
C Zöllner, SA Mousa, O Fischer… - The Journal of …, 2008 - Am Soc Clin Investig
… (7, 8), both of which are usually accompanied by inflammation. In inflammatory pain a
substantial component of opioid analgesia is mediated via opioid receptors on peripheral sensory …
substantial component of opioid analgesia is mediated via opioid receptors on peripheral sensory …
Interactions of inflammatory pain and morphine in infant rats: long-term behavioral effects
… We also hypothesized that preemptive morphine analgesia may have a protective or … to
repetitive inflammatory pain, or morphine analgesia, or both alters the pain thresholds and other …
repetitive inflammatory pain, or morphine analgesia, or both alters the pain thresholds and other …
Peripheral opioids in inflammatory pain
G Watterson, R Howard, A Goldman - Archives of disease in childhood, 2004 - adc.bmj.com
… In this preliminary report we would like to discuss two cases of patients with EB in which
topical morphine provided effective analgesia with apparently no opioid related adverse effects. …
topical morphine provided effective analgesia with apparently no opioid related adverse effects. …
Mechanisms of hyperalgesian and morphine tolerance: a current view of their possible interactions
… with nerve injury and inflammation. Such neuronal plastic … of tolerance to the analgesic
effects of morphine, and a site … /inflammatory hyperalgesia and morphine tolerance. Thus, …
effects of morphine, and a site … /inflammatory hyperalgesia and morphine tolerance. Thus, …
Alterations in attentional mechanisms in response to acute inflammatory pain and morphine administration
JA Boyette-Davis, CD Thompson, PN Fuchs - Neuroscience, 2008 - Elsevier
… These data support our third hypothesis that an appropriate analgesic dose of morphine
would attenuate formalin pain behaviors and result in performance similar to animals that did …
would attenuate formalin pain behaviors and result in performance similar to animals that did …
Opioids in chronic pain
R Przewłocki, B Przewłocka - European journal of pharmacology, 2001 - Elsevier
… receptor agonists such as morphine in this model of experimental inflammatory pain. This
is … that the analgesic efficacy of μ-opioid receptor agonists is increased in inflammation. The …
is … that the analgesic efficacy of μ-opioid receptor agonists is increased in inflammation. The …
Novel endomorphin analogs are more potent and longer-lasting analgesics in neuropathic, inflammatory, postoperative, and visceral pain relative to morphine
AK Feehan, J Morgenweck, X Zhang… - … Journal of Pain, 2017 - Elsevier
… population because of their lack of abuse liability as well as motor impairment compared
with morphine 91 and superior analgesia in inflammatory states as shown in the current study. …
with morphine 91 and superior analgesia in inflammatory states as shown in the current study. …
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