Inflammatory phenotyping predicts clinical outcome in COVID-19

…, REACT COVID investigators Tom Wilkinson Anna … - Respiratory …, 2020 - Springer
… We hypothesise that assessment of inflammatory cytokines in patients with COVID-19 at
presentation to hospital may identify those likely to deteriorate and develop severe disease. …

[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
… focus on hyper-inflammatory host responses in ARDS that play a critical role in the differentiated
development of COVID-19. Furthermore, we discuss inflammation-related indicators that …

Deep phenotyping of the lipidomic response in COVID19 and non‐COVID19 sepsis

H Meng, A Sengupta, E Ricciotti… - Clinical and …, 2023 - Wiley Online Library
… We anticipated that a milder lipidomic inflammatory phenotype might accompany seroconversion
after infection by SARS-CoV-2 in healthy marines, perhaps most evident in those with …

Characterization of the inflammatory response to severe COVID-19 illness

OJ McElvaney, NL McEvoy, OF McElvaney… - American journal of …, 2020 - atsjournals.org
COVID-19 cytokinemia and the inflammatory phenotype of the critically unwell patient with
COVID-19 … presence of immunometabolic reprogramming in patients with severe COVID-19. …

Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study

P Sinha, CS Calfee, S Cherian, D Brealey… - The Lancet …, 2020 - thelancet.com
… In addition to standard laboratory investigations, data were also available for acute
markers of inflammation widely described for COVID-19. These were D-dimer, ferritin, C-reactive …

The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
… mechanistic features indicates that COVID-19 constitutes a new disease … inflammatory
derangements across the range of phenotypes to enable optimum care for patients with COVID-19

Phenotypes of severe COVID-19 ARDS receiving extracorporeal membrane oxygenation

J Zhang, SF Whebell, B Sanderson… - British Journal of …, 2021 - bjanaesthesia.org
phenotypes of COVID-19 patients on ECMO, utilising data available on Day 0 of ECMO
commencement. We hypothesised that distinct phenotypes … to show inflammatory phenotypes in …

COVID-19 phenotypes: leading or misleading?

L Gattinoni, L Camporota… - European Respiratory …, 2020 - Eur Respiratory Soc
… The reasoning put forward by the editorialists seems purely argumentative and inflammatory
editorial: “By prematurely phenotyping patients with COVID-19, we expose ourselves and …

Phenotyping long COVID

R Naeije, S Caravita - European Respiratory Journal, 2021 - Eur Respiratory Soc
… Follow-up studies on COVID-19 patients report on persistently abnormal biology with … of
inflammation, or abnormal magnetic resonance imaging suggesting on-going inflammation or …

Large scale phenotyping of long COVID inflammation reveals mechanistic subtypes of disease

…, ISARIC4C Investigators and the PHOSP-COVID … - medRxiv, 2023 - medrxiv.org
… In conclusion, in a large, hospitalised cohort we found indications of monocytic inflammation
and complement activation in those with continued symptoms 6 months after COVID-19 (fig …