Redox signalling and the inflammatory response in rheumatoid arthritis

LI Filippin, R Vercelino, NP Marroni… - Clinical & Experimental …, 2008 - academic.oup.com
… that enhances the inflammatory response. Many studies have demonstrated a role of ROS
in the pathogenesis of inflammatory chronic arthropathies, such as rheumatoid arthritis. It is …

Pro-and anti-inflammatory cytokines in rheumatoid arthritis

P Isomäki, J Punnonen - Annals of medicine, 1997 - Taylor & Francis
inflammatory response, such as that occurring in rheumatoid … of synovial inflammation in
patients with rheumatoid arthritis. … important in the initiation of the inflammation. This leads to the …

Metalloproteinases, inflammation, and rheumatoid arthritis

FF Mohammed, DS Smookler, R Khokha - Annals of the rheumatic …, 2003 - ard.bmj.com
… of regulating the inflammatory response and affecting diseases such as rheumatoid arthritis.
TIMP-3, in particular, stands out as an important regulator of inflammation with its ability to …

Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts

A Lee, Y Qiao, G Grigoriev, J Chen… - Arthritis & …, 2013 - Wiley Online Library
… Our results suggest that TNFα-induced inflammatory responses are not effectively …
inflammatory signaling in other cell types, such as macrophages. The inflammatory response in …

Immunologic mechanisms in the pathogenesis of rheumatoid arthritis

GS Firestein - JCR: Journal of Clinical Rheumatology, 2005 - journals.lww.com
… Although much is known about the etiology and pathogenesis of rheumatoid arthritis (RA), …
a role for T cells in the inflammatory response characteristic of RA, and based disease …

Inflammation and rheumatoid arthritis

AK Shrivastava, A Pandey - Journal of physiology and biochemistry, 2013 - Springer
… The IL-17 family plays a key role in the regulation of immune and inflammatory response, in
the homeostasis of several tissues, and the progression of autoimmune diseases. In addition…

Pathogenetic insights from the treatment of rheumatoid arthritis

IB McInnes, G Schett - The Lancet, 2017 - thelancet.com
inflammatory response. Novel agents that target interleukin-6 receptor and interleukin 6 have
been shown to be efficacious in rheumatoid arthritis although the overall clinical responses

The interplay between inflammation and metabolism in rheumatoid arthritis

MS Chimenti, P Triggianese, P Conigliaro… - Cell death & …, 2015 - nature.com
… drives the inflammatory response and the mechanisms of angiogenesis. This process
promotes further infiltration of inflammatory cells, production of inflammatory mediators and matrix …

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis

Z Chen, A Bozec, A Ramming, G Schett - … Reviews Rheumatology, 2019 - nature.com
… IL-33 triggers the expansion of ILC2s and activates T H 2 cell-mediated responses 69,70 ,
suggesting a potential role for IL-33 in counteracting inflammatory responses mediated by T H …

Inflammatory markers in patients with rheumatoid arthritis

AK Shrivastava, HV Singh, A Raizada, SK Singh… - Allergologia et …, 2015 - Elsevier
… study indicates that these markers might play a role in inducing inflammatory responses or
mediating anti-inflammatory responses in the pathogenesis of RA, and they correlate with the …