… for whom meropenem was infused continuously. Nevertheless, the predictive performance
of … of other models based on intermittent infusion, extended infusion or a combination of both. …

… serum concentrations were measured using automatic two-dimensional high-performance
liquid … The goodness of fit and visual predictive check (VPC) were used to evaluate the model. …

… (n = 1000 replicate datasets) and prediction-corrected visual predictive checks (VPCs)
were used to evaluate the precision of estimates and the predictive performance of the model. …

… The best predictive performance for intermittent infusion was observed for the O’Jeanson …
Our study revealed the O′Jeanson model as the best-predicting model for intermittent infusion…

… Median and 95% prediction intervals (PI 95 ) of simulated plasma meropenem … male patient
receiving meropenem by continuous infusion in a cooled infuser containing 1% meropenem (…

… a prediction model and to determine whether the mode of infusion was a predictor of … To
determine the performance of this logistic lasso model, the area under the curve (AUC) for the …

… CG-CLCR was found to be a predictive factor for meropenem … In addition, there are many
studies on the effect of infusion … two-dimensional high-performance liquid chromatography …

… of CL Cr estimates, to validate the performance of this formula within a similar cohort of …
for lower respiratory tract infections, the only significant predictor of clinical response among …

… C; CL CG was the least predictive covariate. Neither age, weight, nor … meropenem
concentrations during continuous infusion. The covariate CL CR offers the best predictive …

… optimal loading doses prior to continuous infusion of meropenem in critically ill patients. A
… infusion of 1.5–6 g/24 h with preceding loading doses (administered as 30 min infusion) of …