… , hypertension guidelines do not recommend the time to treat patients with medications.
We … evidence regarding ingestion-time differences of hypertension medications and their …

… -time relative SBP decline. Accordingly, 62 trials published between 1992 and 2020, totaling
6120 hypertensive … 61 ABPM-based ingestion-time hypertension trials of this systematic …

… sleep-time relative BP decline (dipping), and markedly better reduction of CVD morbidity
and mortality when hypertension medications and their combinations are ingested at bedtime …

Full article: Guidelines for the design and conduct of human clinical trials on ingestion-time
differences – chronopharmacology and chronotherapy – of hypertension medications Skip to …

… , and reduced cardiac pathology – when hypertension medications are ingested at-bedtime/…
human clinical trials on ingestion-time differences of hypertension medications. Among the …

… trials that investigated hypertension medications for ingestion-time differences in BP-… totaling
1,508 hypertensive participants concerned the differential ingestion-time dependent effects …

… mean, a novel therapeutic target best achieved with the ingestion of ≥1 hypertension
medications at bedtime, was identified as the most significant predictor of CVD event-free survival. …

… At the time of recruitment, 688 randomised hypertensive … to a treatment-time for ingestion of
hypertension medications. The … thus consisted of 2,012 hypertensive patients without diabetes…

… hypertension referred for observed drug ingestion, 32 were excluded for reasons including
not meeting the criteria for resistant hypertension, having already taken their medication on …

… -time regimens—(i) all hypertension medications ingested … of ≥1 BP-lowering medications
ingested at bedtime—by two-… ingesting all hypertension medications at bedtime at the time …