Inhaled corticosteroids in COPD: a controversy

PJ Barnes - Respiration, 2010 - karger.com
Inhaled corticosteroids (ICS) are now very widely used in high doses in the management
of COPD patients… , ICS provide little or no benefit in COPD patients and may have long-term …

Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
inhaled corticosteroids (ICS) in the treatment of patients with chronic obstructive pulmonary
disease (COPD) … In summary, the effects of ICS on lung function vary between COPD patients

[HTML][HTML] Inhaled corticosteroids

PJ Barnes - Pharmaceuticals, 2010 - mdpi.com
… to the nucleus after activation by corticosteroids [30]. … patients after an inhaled glucocorticoid
and inhaled long-acting β 2 -agonist [31]. This suggests that β 2 -agonists and glucocorticoid

Inhaled corticosteroids and mortality in COPD

C Macie, K Wooldrage, J Manfreda, NR Anthonisen - Chest, 2006 - Elsevier
patients who received inhaled steroids with those who received other respiratory drugs, but
not inhaled steroids… examined the time of receipt of inhaled steroids in relation to fatal events. …

Inhaled corticosteroids in stable COPD patients

B Balbi, M Majori, S Bertacco, G Convertino, A Cuomo… - Chest, 2000 - Elsevier
… the biological response to inhaled steroids in these COPD patients. COPD usually is
characterized … In this scenario, it is conceivable that if steroids work in patients with COPD, their …

Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD

D Price, B Yawn, G Brusselle, A Rossi - Primary Care Respiratory …, 2013 - nature.com
patients with COPD. This article is based on a review of the literature (PubMed: COPD AND
inhaled corticosteroids… evidence for the efficacy and safety of ICS use in patients with COPD. …

Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomes

G Gartlehner, RA Hansen, SS Carson… - The Annals of Family …, 2006 - Annals Family Med
… -benefit ratio of inhaled corticosteroid treatment for COPD by … of inhaled corticosteroid treatment
in patients with COPD with … risk-benefit ratio of inhaled corticosteroid treatment for COPD. …

Inhaled corticosteroids in COPD: the clinical evidence

P Ernst, N Saad, S Suissa - European Respiratory Journal, 2015 - Eur Respiratory Soc
… in tackling COPD. However, far greater amounts of money are spent on drug therapy for COPD
… supporting treatment with inhaled corticosteroids (ICS) in COPD, including treatment with …

Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease

DD Sin, L Wu, JA Anderson, NR Anthonisen, AS Buist… - Thorax, 2005 - thorax.bmj.com
… homogeneous dosing schedules for specific inhaled corticosteroids, we could not determine
whether different doses produced differential outcomes in COPD patients. Finally, as with …

Inhaled corticosteroids for chronic obstructive pulmonary disease

M Cazzola, P Rogliani, L Novelli… - Expert opinion on …, 2013 - Taylor & Francis
… There is now solid evidence suggesting that oxidative and nitrative stress in the lungs of
COPD patients play a key role in mediating corticosteroid unresponsiveness in these patients