Inhibition of MAPK Kinase Signaling Pathways Suppressed Renal Cell Carcinoma Growth and Angiogenesis In vivo
… RCC cells was dramatically inhibited by … inhibition of proliferation of endothelial cells in
vitro. Our results suggest that suppression of one or more MAPK signaling pathways may inhibit …
vitro. Our results suggest that suppression of one or more MAPK signaling pathways may inhibit …
Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells
AA Stone, TC Chambers - Experimental cell research, 2000 - Elsevier
… vival and cell death, we examined the extent and kinetics of activation of JNK, ERK, and p38
MAPKs in response to treatment of KB-3 carcinoma cells with several microtubule inhibitors. …
MAPKs in response to treatment of KB-3 carcinoma cells with several microtubule inhibitors. …
Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells
DB Reardon, JN Contessa, RB Mikkelsen, K Valerie… - Oncogene, 1999 - nature.com
… cell proliferation and potentiating apoptosis. In summary, this data demonstrates that both
MAPK … downstream activation of MAPK which may affect the radiosensitivity of carcinoma cells. …
MAPK … downstream activation of MAPK which may affect the radiosensitivity of carcinoma cells. …
Inhibition of Aurora-A suppresses epithelial–mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
XB Wan, ZJ Long, M Yan, J Xu, LP Xia, L Liu… - …, 2008 - academic.oup.com
… MAPK phosphorylation and induced EMT ( 11 ). Conversely, inhibition of MAPK upstream
component MEK by inhibitor U0126 reversed this phenotype and reconstructed the tight cell …
component MEK by inhibitor U0126 reversed this phenotype and reconstructed the tight cell …
… -induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2 …
M Hagan, L Wang, JR Hanley, JS Park… - Radiation …, 2000 - meridian.allenpress.com
… Further, after irradiation, MAPK inhibition reduces clonogenic … cells become dependent on
MAPK activation for cell cycle progression. MAPK inhibition results in profound apparent cell …
MAPK activation for cell cycle progression. MAPK inhibition results in profound apparent cell …
PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways
R Gedaly, P Angulo, J Hundley, MF Daily… - Anticancer …, 2010 - ar.iiarjournals.org
… The novel anticancer agent sorafenib is a multi-kinase inhibitor of more than a dozen … been
shown to inhibit tumor cell proliferation by blocking the Ras/Raf/MAPK pathway and to inhibit …
shown to inhibit tumor cell proliferation by blocking the Ras/Raf/MAPK pathway and to inhibit …
The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer
HY Yong, MS Koh, A Moon - Expert opinion on investigational …, 2009 - Taylor & Francis
… p38α and p38β specifically induced the malignant phenotype of squamous cell
carcinoma cells by regulating cell survival, proliferation and invasion, suggesting these p38 …
carcinoma cells by regulating cell survival, proliferation and invasion, suggesting these p38 …
[HTML][HTML] Rapid inhibition of MAPK signaling and anti-proliferation effect via JAK/STAT signaling by interferon-α in hepatocellular carcinoma cell lines
K Inamura, Y Matsuzaki, N Uematsu, A Honda… - … (BBA)-Molecular Cell …, 2005 - Elsevier
… IFN-α via the MAPK pathway in human HCC cell lines. Using … and ERK and blocked the
inhibition of phosphorylation of MEK … the MAPK pathway with rapid inhibition of MAPK signaling …
inhibition of phosphorylation of MEK … the MAPK pathway with rapid inhibition of MAPK signaling …
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-β-mediated Smad-dependent growth inhibition of human breast carcinoma cells in …
AK Kamaraju, AB Roberts - Journal of Biological Chemistry, 2005 - ASBMB
… We demonstrate that activation of the p38 MAP kinase pathway is necessary for the full …
/ROCK and p38 MAPK pathways as necessary for TGF-β-mediated growth inhibition, but …
/ROCK and p38 MAPK pathways as necessary for TGF-β-mediated growth inhibition, but …
MALT1 inhibition of oral carcinoma cell invasion and ERK/MAPK activation
T Chiba, Y Soeno, Y Shirako, H Sudo… - Journal of Dental …, 2016 - journals.sagepub.com
… These suggest that loss of MALT1 expression facilitates the carcinoma invasion. In the present
study, we examined a role of MALT1 in oral carcinoma cell invasion by in vitro assays and …
study, we examined a role of MALT1 in oral carcinoma cell invasion by in vitro assays and …
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- hepatocellular carcinoma cells
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- carcinoma cell lines
- human hepatocellular carcinoma cells interferon α
- carcinoma cells lymphoid tissue
- carcinoma cell invasion malt1 inhibition
- map kinase inhibition prostate carcinoma cells
- human breast carcinoma cells
- carcinoma cell proliferation ras raf mapk
- carcinoma cells microtubule inhibitors
- carcinoma cells inhibition of the mitogen
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- carcinoma cells sorafenib inhibition
- breast carcinoma cells growth inhibition
- carcinoma cells inhibition of tgf β