… for better approaches to inhibitor design. Here, we discuss alternative strategies that might
lead to better p38 inhibitors, including non-ATP-competitive inhibitors and inhibitors that are …

… The p38 MAPK pathway may be disproportionately … of p38 MAPK, a mechanism shown
to promote the lifecycle of respiratory viruses including SARS-CoV. Unrestrained p38 MAPK …

… In this review, we summarize the unique characteristics of p38 MAPK and highlight its … use
of p38 MAPK inhibitors. We also summarize and present the list of p38 MAPK inhibitors based …

… Interestingly, we show contrasting effects of p38 MAPK inhibition as compared to aspirin
inhibition on platelet aggregation in response to collagen. Blockade of TXA2 production by …

… the p38 MaPK pathway is involved in 5-fu resistance in colorectal cancer cells. 5-fu only or
5-fu combined with a p38 MaPK pathway inhibitor (… results showed that p38 MaPK inhibitor …

… in cellular processes and (4) the establishment of the mechanism by which the pyridinylimidazole
p38 MAP kinase inhibitors inhibit enzyme activity. It is now known that there are four …

… if the p38 MAPK pathway affects renal cyst and fibrosis in inv mutant mice. We examined p38
MAPK … and then treated inv/inv, invΔC mice with a selective p38 MAPK inhibitor, FR167653. …

… It seems plausable that blunting of the host response via inhibition of the p38 MAPK
pathway may be a frequent theme in persistent bacterial infections, particularly by intracellular …

Mitogen‐activated protein (MAP) kinases have been implicated as important mediators of
the inflammatory response. Here we report that c‐Jun NH 2 ‐terminal kinase (JNK), …

… Inhibiting the MAPK pathway as an anti-inflammatory therapy might not necessarily be best
achieved by inhibiting p38 MAPK … As discussed below, the pathway is involved in processes …