… become a standard frontline strategy in North America … first-line therapy (m7–Follicular
Lymphoma International Prognostic Index [m7-FLIPI]) and for poor outcomes after frontline therapy …

… Multiple studies have shown increased mortality risk in patients with follicular lymphoma (FL)
who have progression of disease within 24 months of initial treatment (POD24) versus …

… therapy in 5.6%, chemotherapy in 3.2% and rituximab with chemotherapy in 51.9%. A current
strategy for the initial management … benefits of various management strategies are needed …

… Less than 20% of patients with follicular lymphoma (FL) present with Ann Arbor Stage I or II
… exist, however radiation therapy is considered the standard of care for early-stage disease …

… management requires an understanding of the available therapeutic options for first‐line
treatment … Thus, this work reviews for clinicians the contemporary data in follicular lymphoma, …

… The current strategy of therapy in follicular lymphomas with a high tumour burden comprises
initial immunochemotherapy for achieving a complete or partial remission, followed by 2 …

… The diversity of clinical scenarios, the flood of data derived from phase II studies, and the
lack of randomized studies comparing treatment strategies preclude firm recommendations and …

… Follicular lymphoma (FL) was first described in 1925 as a benign disorder called Brill-Symmers
disease, but within a couple of decades, it was recognized as a malignancy typical of …

… initiation, it is important to implement a dynamic strategy that ensures the early identification
… to offer them innovative therapeutic strategies. The nuanced management of FL is now well …

… The varied presentation at diagnosis and frequent lack of significant symptoms result in
stark differences in initial management strategies, from observation to chemoimmunotherapy. …