[HTML][HTML] COVID 19: a clue from innate immunity

D Birra, M Benucci, L Landolfi, A Merchionda, G Loi… - Immunologic …, 2020 - Springer
The recent COVID-19 pandemic has had a significant impact on our lives and has rapidly
expanded to reach more than 4 million cases worldwide by May 2020. These cases are …

[HTML][HTML] Innate immunity in protection and pathogenesis during coronavirus infections and COVID-19

RKS Malireddi, BR Sharma… - Annual Review of …, 2024 - annualreviews.org
… Here, we discuss the innate immune mechanisms that sense coronaviruses, with a focus on
… in severe cases of COVID-19, contributing to cytokine storm, inflammation, long-COVID, and …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
… In summary, because the innate immune response harbors the capacity to induce broad-…
drives much of COVID-19 pathology, therapeutic targeting of the innate immune system in SARS…

[HTML][HTML] COVID-19 and the human innate immune system

JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
innate immune system components among humans is a main contributor to the heterogeneous
disease courses observed for coronavirus disease 2019 (COVID-19)… in innate immunity is …

[HTML][HTML] Heightened innate immune responses in the respiratory tract of COVID-19 patients

Z Zhou, L Ren, L Zhang, J Zhong, Y Xiao, Z Jia, L Guo… - Cell host & …, 2020 - cell.com
… To understand the cytokine profile in BALF from the COVID-19 patients, we assigned DEGs
into … These observations suggested that the exuberant inflammation in COVID-19 could be …

[HTML][HTML] Covid-19: perspectives on innate immune evasion

N Taefehshokr, S Taefehshokr, N Hemmat… - Frontiers in …, 2020 - frontiersin.org
… multiple aspects of innate immunity, with severe acute respiratory syndrome coronavirus 2
(SARS-… This review discusses the known host innate immune response and immune evasion …

[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
… We also highlight how innate immune sensing and activation can lead to pathology, … in
COVID-19. Moreover, we discuss immunomodulatory therapeutic strategies in COVID-19 and …

[PDF][PDF] Innate immunity in COVID-19: Drivers of pathogenesis and potential therapeutic targets

V Ruenjaiman, N Hirankarn… - Asian Pacific journal of …, 2021 - apjai-journal.org
… Here, we have focused on the innate immune responses to … innate immune response
to SARS-CoV-2 and its detrimental effect, if not properly controlled in severe cases of COVID-19

Innate immunity in COVID-19 patients mediated by NKG2A receptors, and potential treatment using Monalizumab, Cholroquine, and antiviral agents

A Yaqinuddin, J Kashir - Medical hypotheses, 2020 - Elsevier
… -CoV-2 overrides innate immune response of the host is by … in functional exhaustion of the
immune response against the viral … COVID-19 have a severely compromised innate immune

Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics

K Chumakov, MS Avidan, CS Benn… - Proceedings of the …, 2021 - National Acad Sciences
… An LAV designed to induce adaptive immunity targeting a particular pathogen may also
induce innate immunity that mitigates other infectious diseases, including COVID-19, as well as …