… The mechanisms that regulate the host response to … and innate immune receptors in
regulating noninfectious … Work from our laboratory has shown that failure to remove matrix …

… Hence, specific ECM and ECM-associated proteins possess previously unknown
transcriptional and post-transcriptional regulatory activities, which fine-tune the innate immune …

… Innate immune mechanisms may drive such chronic … derived from innate cells [Macrophages,
innate lymphoid cells (ILCs… matrix (ECM), but they are driven by innate rather than adaptive …

… The picture that has emerged for the key roles of MMPs in regulating chemokine activity
and consequently regulating innate immunity is as follows. The neutrophil-specific MMPs …

… matrix and thereby regulate cell migration and tissue repair. In addition, MMP-7 has an important
role in the maintenance of innate immunity in … Consistent with its role in innate immunity, …

… Hyaluronic acid (HA), a non-sulfated GAG without a protein core, is capable of regulating
the innate immune response via TLRs through different mechanisms which are dependent on …

… Innate immunity has an important role in regulating inflammatory, remodelling … innate
immunity involved in tissue injury, SAP was shown to be involved in wound healing and regulation …

… innate immune system and hemostasis, and suggest that recognition of microbes and
extracellular matrix are … spreading [41] and regulating local inflammation by acting as a scaffold for …

▪ Abstract C reactive protein, the first innate immunity receptor identified, and serum amyloid
P component are classic short pentraxins produced in the liver. Long pentraxins, including …

… Instead, proinflammatory mediators, particularly suggestive of innate immune responses
and factors affecting extracellular matrix (ECM) remodeling, were prominent (14, 29). A number …