… (TSC-mTOR) pathway regulated inflammatory responses after bacterial … Inhibition of mTOR
by rapamycin promoted production of … of the mTOR pathway limits inflammatory responses by …

… , and mast cells play central roles in the innate immune response. This figure highlights the
regulation of diverse innate immune cells by TSC–mTOR, which are discussed in this review. …

… In the current study, we elucidate a role for mTOR in … response to IL-4, whereas the
inflammatory response to LPS is enhanced. Aberrant polarization is due, at least in part, to mTORC1-…

… status to dictate and optimize the inflammatory response. A detailed understanding of how
mTOR metabolically coordinates effector responses by myeloid cells will provide important …

… study, Weichhart et al. investigated how mTOR activity in phagocytes regulates the innate …
that the TSC–mTOR pathway is a crucial regulator of the innate inflammatory response, which …

… immunoregulatory context by controlling innate and adaptive immune responses. In this …
analyze the impact of the TSC–mTOR pathway downstream of PI3K with regard to regulation of …

… (mTOR) is a master regulator of the inflammatory response in … also activates mTORC1 by
inhibiting the TSC complex function [… -inflammatory effects of mTOR inhibition in innate immune …

… of mTOR signalling in macrophages and DCs (dendritic cells), two cardinal phagocytes of the
innate immune system, to regulate immune responses … to integrate the TSC/mTOR pathway …

… Collectively, receptor engagement leads to a coordinated activation of PI3K/Akt, TSC-1/2 … ,
wound healing, regulation of innate and adaptive immune responses and peripheral tolerance.…

… –mTOR signaling to regulate innate inflammatory responses. We found that TLR ligands or
environmental stress activates the TSC2-mTOR … the activation of mTOR via the TSC complex. …