Cytotoxic FCER1G+ innate-like T cells: new potential for tumour immunotherapy

E Morrish, J Ruland - Signal Transduction and Targeted Therapy, 2022 - nature.com
… T lymphocytes (CTLs) that can recognise mutated cancer cell antigens and thereby enable
tumour cell killing. Yet, a significant cohort of cancer … anti-cancer immunomechanisms. Recent …

Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells

B Ruf, B Heinrich, TF Greten - Cellular & molecular immunology, 2021 - nature.com
immunotherapy for HCC, we explore the immunobiology of HCC, with a focus on innate and
innate-… Therefore, to target these cells for liver cancer immunotherapy, our understanding of …

Natural killer cells and other innate lymphoid cells in cancer

L Chiossone, PY Dumas, M Vienne… - Nature Reviews …, 2018 - nature.com
cancer, ILC2s secrete IL-13 and stimulate MDSCs, thereby mediating a detrimental tolerogenic
pathway that could be used as a novel therapeutic target in cancer immunotherapy 77 . …

Pattern recognition receptors of innate immunity and their application to tumor immunotherapy

T Seya, H Shime, T Ebihara, H Oshiumi… - Cancer …, 2010 - Wiley Online Library
… Up until now, the effectiveness of cancer immunotherapy has been primarily evaluated based
on tumor regression and the survival prognosis of patients. A representative study involved …

[HTML][HTML] Nanomaterials for modulating innate immune cells in cancer immunotherapy

QV Le, G Yang, Y Wu, HW Jang… - Asian Journal of …, 2019 - Elsevier
Cancer immunotherapy has been intensively investigated in both preclinical and clinical …
tumor cells, cancer immunotherapy is based on the ability of the immune system to fight cancer. …

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

B Farhood, M Najafi… - Journal of cellular …, 2019 - Wiley Online Library
… work between cells of innate immunity including dendritic cells (DCs… cancer cells. Exogenous
reactivation and/or priming of CD8 + T cells can be possible using rational immunotherapy

Chimeric antigen receptor-and natural killer cell receptor-engineered innate killer cells in cancer immunotherapy

C Zhang, Y Hu, W Xiao, Z Tian - Cellular & Molecular Immunology, 2021 - nature.com
… CAR- and NKR-engineered innate killer cells for use in cancer immunotherapy Innate
lymphocytes constitute a heterogeneous group of cells that includes innate lymphoid cells (ILCs, …

[图书][B] Novel approaches to targeting innate immunity for cancer immunotherapy

PH Lizotte - 2015 - search.proquest.com
innate populations, can we develop novel immunotherapies that target them and awaken
their inherent ability to become inflammatory and immunostimulatory? I believe this is also true …

Chimeric antigen receptor engineered innate immune cells in cancer immunotherapy

C Lin, J Zhang - Science China Life Sciences, 2019 - Springer
… to a revolutionary innovation in cancer immunotherapy. As an important type of … immunotherapy.
However, engineered T cells seem to hit their bottleneck when resistance of cancerous

The role of innate lymphoid cells in cancer development and immunotherapy

R Sugimura, CY Wang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
… of innate lymphoid cells (ILCs)—a new group of innate immune cells—we are seeing a
brand-new collection of cells that communicate with both the innatecancer immunotherapies. …