Contribution to tumor angiogenesis from innate immune cells within the tumor microenvironment: implications for immunotherapy

A Albini, A Bruno, DM Noonan, L Mortara - Frontiers in immunology, 2018 - frontiersin.org
… Despite the strong clinical success of cancer immunotherapy with checkpoint inhibitors and
other immune modulating agents, most patients still do not experience a durable response (…

Cancer immunotherapy: the past, the present and the future

CR Parish - Immunology and cell biology, 2003 - Wiley Online Library
innate response must be involved. Another interesting implication of the involvement of innate
immunity in cancer … of Coley's approach to cancer immunotherapy. In this regard, it is now …

Enhancing cancer immunotherapy via activation of innate immunity

JL Goldberg, PM Sondel - Seminars in oncology, 2015 - Elsevier
… immune cells have been successfully augmented as part of an immunotherapy regimen.
In … immunotherapy of cancer will likely involve components of innate immune stimulation. …

[HTML][HTML] Immunotherapy targeting inhibitory checkpoints: The role of NK and other innate lymphoid cells

E Munari, L Quatrini, C Ciancaglini, A Eccher… - Seminars in …, 2022 - Elsevier
… and also as a potential candidate for cancer immunotherapy. TIM-3 acts as a negative
regulator of NK cell function and its upregulation in cancer patients has been associated with an …

At the Bedside: Innate immunity as an immunotherapy tool for hematological malignancies

F Locatelli, P Merli, S Rutella - Journal of Leukocyte Biology, 2013 - academic.oup.com
… We will also analyze the peculiarities of the γδ T lymphocyte … the optimal clinical exploitation
of these cells of innate immunity. … these properties and optimize cancer immunotherapy? …

Cancer immunotherapy: activating innate and adaptive immunity through CD40 agonists

GL Beatty, Y Li, KB Long - Expert review of anticancer therapy, 2017 - Taylor & Francis
cancer immunotherapy relies on an alignment of the innate and adaptive arms of the immune
system. A key molecule involved in bridging innate and … Within the innate immune system, …

Innate immune mediators in cancer: between defense and resistance

P Berraondo, L Minute, D Ajona… - Immunological …, 2016 - Wiley Online Library
… In the current rush to advance cancer immunotherapy, innate … failure of cancer
immunotherapies, the role of innate immune … , myeloid leukocytes, and innate lymphocytes are …

Innate immunity based cancer immunotherapy: B16-F10 murine melanoma model

V Caisová, A Vieru, Z Kumžáková, S Glaserová… - BMC cancer, 2016 - Springer
Cancer immunotherapy based on the stimulation of innate … Further improvement of cancer
immunotherapy based on the use of … This innate immunity based cancer immunotherapy was …

Innate immune defense mechanisms by myeloid cells that hamper cancer immunotherapy

E Lebegge, SM Arnouk, PMR Bardet, M Kiss… - Frontiers in …, 2020 - frontiersin.org
… of innate effector mechanisms performed by myeloid cells during cancer development and
progression. Noteworthy, effector mechanisms that are initially deployed by innate myeloid …

Natural killer cells in innate immunity and cancer

B Becknell, MA Caligiuri - Journal of immunotherapy, 2008 - journals.lww.com
… CD56 + CD3 − lymphocytes that constitute 1 component of the innate immune system. NK …
Recent studies have implicated NK cells in bridging the innate and adaptive immune response…