… William Coley, an American bone surgeon, is credited with pioneering work in the field of
cancer immunotherapy. In the 1890s, he noted that patients with sarcoma who developed …

… NK cell lines have been used in cancer immunotherapy because of their increased expansion
ability in vitro and their relatively simple cultivation conditions. To date, there are seven …

… Therefore, targeting TLRs with agonists for cancer immunotherapy will not be a
straightforward process. Further understanding the key factors of TLR signaling involved in …

… activation initiated by innate immunity is missing. Here, we demonstrate that effective
cancer immunotherapy requires phased activation of both immune parts, innate immunity and …

… Cells of the innate immunity play an important role in tumor immunotherapy. Thus, NK cells
… T lymphocytes. Additional approaches in which NK cells may represent an important tool for …

… Among the most potent antitumor cytolytic mediators are γδ T cells, innate-like
lymphocytes that recognize their targets independently of major histocompatibility complex (MHC)–…

… inactivated ALI could activate innate and adoptive antitumor immune response. It would be
a simple, effective and secured method for cancer immunotherapy. © 2008 Wiley-Liss, Inc. …

… We find a requirement for innate lymphocytes (ILC), as treatment is not effective in animals
… potential role for innate lymphoid cells in the efficacy of chemo-immunotherapy using tumor-…

… for cancer immunotherapy, either alone or in combination with cytokine-based treatment. The
exciting prospects of targeting the upstream innate … cancer immunotherapeutic resistance. …

… innate immune system are at the forefront of the body's defense systems and evidence
suggests that the infiltration and cytotoxicity of NK cells in the cancer … in cancer immunotherapy. …