Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity

L Hou, C Tian, Y Yan, L Zhang, H Zhang, Z Zhang - ACS nano, 2020 - ACS Publications
… In summary, an innate immunity nanoactivator for improving immunotherapeutic efficacy
of the cGAS/STING pathway was developed, in which DOX was first encapsulated into APMP …

The emergence of natural killer cells as a major target in cancer immunotherapy

F Souza-Fonseca-Guimaraes, J Cursons… - Trends in …, 2019 - cell.com
… NK cells possess the innate ability to detect transformed cells, and thus, … immunotherapy
response rates. Here, we review the emerging role of NK cell-based cancer immunotherapies

[PDF][PDF] An efficient combination immunotherapy for primary liver cancer by harmonized activation of innate and adaptive immunity in mice

L Wen, B Xin, P Wu, CH Lin, C Peng, G Wang… - …, 2019 - Wiley Online Library
… nism-based combinatorial immunotherapeutic protocols may shift the paradigm in liver
cancer treatment by coordinating maximal activation of multiple innate and adaptive immune …

The critical role of type‐1 innate and acquired immunity in tumor immunotherapy

H Ikeda, K Chamoto, T Tsuji, Y Suzuki… - Cancer …, 2004 - Wiley Online Library
… Therefore, we conclude that the activation of type-1 innate and acquired immunity is crucial
… A new era for cancer immunotherapy based on the genes that encode cancer antigens. …

[HTML][HTML] Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

H Raskov, A Orhan, JP Christensen… - British journal of cancer, 2021 - nature.com
… The functions of, and interactions between, the innate and … backbone of current successful
cancer immunotherapies. Immune-… effectors in cancer and cancer immunotherapy, cytotoxic T …

Cancer immunotherapy via dendritic cells

K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
… The cells and molecules of the innate immune system use non-clonal recognition receptors,
… information to lymphocytes. Thus, DCs provide an essential link between the innate and …

[HTML][HTML] A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion

SM Jin, YJ Yoo, HS Shin, S Kim, SN Lee… - Nature …, 2023 - nature.com
… cells, resulting in suboptimal cancer immunotherapy. Here we … integrate two waves of
innate immune stimuli, resulting in … of innate immunity for enhanced cancer immunotherapy. …

[HTML][HTML] Harnessing the power of invariant natural killer T cells in cancer immunotherapy

M Bedard, M Salio, V Cerundolo - Frontiers in immunology, 2017 - frontiersin.org
… in cancer and how these cells can be manipulated for the purpose of cancer immunotherapy.
… Invariant natural killer T cells are considered innate-like lymphocytes as they exhibit …

[图书][B] Innate immune regulation and cancer immunotherapy

RF Wang - 2012 - books.google.com
… to pathogens and cancer. Chapters 2 and 3 introduce innate lymphocytes, including NKT
and gamma–delta T cells and their roles in innate immune response to cancer. Chapters 4 and …

Cancer and the immune system: the history and background of immunotherapy

M Abbott, Y Ustoyev - Seminars in oncology nursing, 2019 - Elsevier
… of cancer cells with the immune system provides foundational knowledge for understanding
cancer immunotherapy. … Innate immunity is limited to release of cytokines that recruit immune …