Retinoic acid inhibits expression of TNF‐α and iNOS in activated rat microglia
… In the present study, RA inhibits the synthesis and release of both TNF-α and iNOS in the
activated microglia and the synthesis appears to be regulated at the transcriptional and …
activated microglia and the synthesis appears to be regulated at the transcriptional and …
TNF-α modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis
J Nandi, B Saud, JM Zinkievich, Z Yang… - Molecular and Cellular …, 2010 - Springer
… on the action of PDE inhibitors on TNF-α and IL-1β levels reach variable conclusions [18,
28–31], our results show that PDE inhibitors decrease DAI less compared to TNF-Ab and HBO …
28–31], our results show that PDE inhibitors decrease DAI less compared to TNF-Ab and HBO …
The pro‐inflammatory cytokine TNF‐α inhibits lymphatic pumping via activation of the NF‐κB‐iNOS signaling pathway
Y Chen, S Rehal, S Roizes, HL Zhu, WC Cole… - …, 2017 - Wiley Online Library
… in TNF-α-treated vessels upon selective inhibition of iNOS with … the preeminent role of iNOS
in the TNF-α-induced decrease … iNOS-dependent impairment of arterial contractility by TNF-α.…
in the TNF-α-induced decrease … iNOS-dependent impairment of arterial contractility by TNF-α.…
Inhibition of TNF-α improves indomethacin-induced enteropathy in rats by modulating iNOS expression
B Saud, J Nandi, G Ong, S Finocchiaro… - Digestive diseases and …, 2005 - Springer
… iNOS expression and upregulates inflammatory responses. We evaluated the relationship
between TNF-α and iNOS … In the present study, we investigated the effect of TNF-α inhibition …
between TNF-α and iNOS … In the present study, we investigated the effect of TNF-α inhibition …
Minocycline inhibits apoptotic cell death via attenuation of TNF‐α expression following iNOS/NO induction by lipopolysaccharide in neuron/glia co‐cultures
SM Lee, TY Yune, SJ Kim, YC Kim, YJ Oh… - Journal of …, 2004 - Wiley Online Library
… by inhibiting NO production and iNOS induction after LPS-treatment. Most notably, we
determined that iNOS/NO signaling cascades were mediated by TNF-α … on the inhibition of TNF-α …
determined that iNOS/NO signaling cascades were mediated by TNF-α … on the inhibition of TNF-α …
New natural pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) and iNOS inhibitors identified from Penicillium polonicum through in vitro and in vivo studies
… iNOS have been found to be concomitant with several chronic inflammatory diseases and
hence targeting their inhibition … in RAW 264.7 cells), it exhibited inhibition of TNF-α, IL-6 and IL-…
hence targeting their inhibition … in RAW 264.7 cells), it exhibited inhibition of TNF-α, IL-6 and IL-…
Role of iNOS in osteoarthritis: Pathological and therapeutic aspects
… Many of these iNOS inhibitors hold promise for the development of new, disease-modifying
therapies for OA; however, attempts to demonstrate their success in clinical trials are not yet …
therapies for OA; however, attempts to demonstrate their success in clinical trials are not yet …
Involvement of iNOS-dependent NO production in the stimulation of osteoclast survival by TNF-α
… Our experiments with PI 3-kinase and MEK inhibitors suggested that the iNOS induction
by TNF-α in mature osteoclasts was independent on the PI 3-kinase/Akt and MEK/ERK …
by TNF-α in mature osteoclasts was independent on the PI 3-kinase/Akt and MEK/ERK …
Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl4-intoxicated mice
… Our results suggest that iNOS mediates acute CCl 4 -induced liver injury and its inhibition
by berberine exerts beneficial effects in the prevention of acute hepatic damage. …
by berberine exerts beneficial effects in the prevention of acute hepatic damage. …
Connecting TNF-α signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by …
R Medeiros, RDS Prediger, GF Passos… - Journal of …, 2007 - Soc Neuroscience
… The iNOS inhibition or the iNOS genetic deletion significantly protected mice from Aβ 1–40
-induced impairment of learning and memory. These protective effects might be explained by …
-induced impairment of learning and memory. These protective effects might be explained by …
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