… phenotype and may induce macrophage specific cell death. … inhibition of macrophage
infiltration of adipose tissue via … insulin sensitivity in obese individuals with insulin resistance …

… leads to the onset of insulin resistance and type 2 diabetes mellitus. … of macrophages in
adipose tissue along with production of inflammatory cytokines. Adipose tissue macrophages (…

… an important role in the development of insulin resistance and type 2 Diabetes in … by tissue
resident immune cells, with particular attention being focused on adipose tissue macrophages …

… been causally linked to adipose tissue macrophages (ATMs) … macrophage phenotype and
function in human subcutaneous and omental adipose tissue in relation to insulin resistance …

… Macrophages are the primary immune cells involved in … of the additional roles of adipose
tissue macrophages (ATMs) … extended crosstalk within adipose tissue between perivascular …

… IR, with a progressive infiltration of macrophages into obese adipose tissue. These adipose
tissue macrophages are referred to as classically activated (M1) macrophages. They release …

… macrophage recruitment into adipose tissue in promoting the development of insulin resistance
… the emerging role of macrophages in mediating healthy adipose tissue expansion during …

… the relationship between adipose tissue macrophage burden and inflammation … adipose
tissue inflammation and macrophage burden and systemic inflammation on whole body insulin …

… insulin resistance in mice precedes macrophage accumulation and inflammation in
adipose tissue… combines genetically induced, adipose-specific insulin resistance (mTORC2-knockout…

… Figure 2 Factors regulating macrophage polarity and insulin resistance in adipose tissue.
Under lean conditions, adipocytes secrete factors, such as interleukin (IL)-13, that promote …