Persistent organic pollutant exposure leads to insulin resistance syndrome

J Ruzzin, R Petersen, E Meugnier… - Environmental …, 2010 - ehp.niehs.nih.gov
… In this study, we demonstrate for the first time a causal relationship between POPs and insulin
resistance in rats. In vivo, chronic exposure to low doses of POPs commonly found in food …

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

PJ Klover, TA Zimmers, LG Koniaris, RA Mooney - Diabetes, 2003 - Am Diabetes Assoc
… mechanism to contribute to the insulin resistance of obesity. The … as chronic exposure to
IL-6 inhibits insulin action in vivo. This implicates IL-6 as a contributor to the insulin resistance of …

Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance

S Lim, SY Ahn, IC Song, MH Chung, HC Jang, KS Park… - PloS one, 2009 - journals.plos.org
… hermaphroditism of exposed male frogs [23]. In the present study, we found that chronic
exposure to low concentrations of ATZ induced abdominal obesity and insulin resistance in rats …

Chronic tobacco exposure by smoking develops insulin resistance

S Mukharjee, S Bank, S Maiti - Endocrine, Metabolic & Immune …, 2020 - ingentaconnect.com
… and chronic exposure to nicotine show decreased insulin … L concentration nicotine exposure
inhibits insulin secretion in … might be due to the exposure of nicotine via the nAChRs [58, …

Chronic exposure to PCBs (Aroclor 1254) exacerbates obesity-induced insulin resistance and hyperinsulinemia in mice

SL Gray, AC Shaw, AX Gagne… - Journal of Toxicology and …, 2013 - Taylor & Francis
… Our results demonstrate that chronic exposure to a PCB mixture (Aroclor 1254) is … and
exacerbates insulin resistance in obese mice without inducing changes in body weight. Chronic

Emerging links between cadmium exposure and insulin resistance: human, animal, and cell study data

A Buha, D Đukić-Ćosić, M Ćurčić, Z Bulat, B Antonijević… - Toxics, 2020 - mdpi.com
… in plasma insulin-like growth factor 1 (IGF-I) and insulin-like … Insulin resistance in the muscle
of rats chronically exposed to … Studies with rodents exposed to Cd have shown decreased …

Persistent organic pollutant-mediated insulin resistance

YA Kim, JB Park, MS Woo, SY Lee, HY Kim… - International Journal of …, 2019 - mdpi.com
… and DM type 2 or insulin resistance was not an important issue in the early 20th century,
although it has been suggested for people who were constantly and chronically exposed to low …

Chronic exposure to environmental level phenanthrene induces non-obesity-dependent insulin resistance in male mice

L Fang, J Guo, Q Wang, K Ou, M Zou, L Lv… - Environmental …, 2020 - ACS Publications
… In this study, chronic exposure to environmentally relevant doses of Phe caused nonobese
insulin resistance in male KM mice. The underlying mechanism might be the disruption of …

Long-term exposure to ambient fine particulate pollution induces insulin resistance and mitochondrial alteration in adipose tissue

X Xu, C Liu, Z Xu, K Tzan, M Zhong… - Toxicological …, 2011 - academic.oup.com
… We have previously shown that chronic exposure to ambient … insulin resistance through
alterations in inflammatory pathways. In this study, we evaluated the effects of PM 2.5 exposure

Dexamethasone regulates the glucose transport system in primary cultured adipocytes: different mechanisms of insulin resistance after acute and chronic exposure

WT GARVEY, TP Huecksteadt, R MONZON… - …, 1989 - academic.oup.com
… mechanisms of insulin resistance are operative after chronic … severe insulin resistance than
that after short term exposure. … of insulin resistance that accompany both acute and chronic