… Here, we review several mechanisms proposed to explain the pathogenesis of insulin
resistance—mainly, the development of insulin resistance from ectopic lipid accumulation, the …

… a greater risk of developing diabetes with insulin resistance as the cornerstone. Researchers
… Insulin resistance is common in individuals with obesity or T2DM, in which insulin action is …

… is that insulin resistance induces a vicious … insulin resistance. Here I suggest that reversing
this cycle via suppression of the lipogenic transcription factor SREBP-1c is a common thread …

… pathological developments, but also possibly common, impaired metabolic pathways. One
such trait is insulin resistance which commonly occurs in peripheral tissues in obesity and …

… Insulin action was quantified both at the whole-body level … the role of skeletal muscle in
this model of insulin resistance. … of insulin action in surgery-associated insulin resistance as …

… We present a clinical approach to the treatment of syndromic insulin resistance. The
study of … population with obesity, insulin resistance, and diabetes. (Endocr Pract. 2012; 18:763-771) …

… of insulin resistance than those of primary insulin signalling defects, suggesting that
lipodystrophy could be a relevant model for common … contributor to prevalent insulin resistance. …

… of measures of insulin resistance with both blood pressure and sympathetic activity in this
study and in other clinical and population-based studies. The effect of insulin and the …

… Moreover, in DIO (diet-induced obesity)-mice, T- or B-cell depletion or genetic deficiency
resulted to ameliorate insulin resistance, confirming a tight thread surrounding adaptive …

… highlight the multifactorial nature of insulin resistance. A call to action … approach for
managing insulin resistance, offering … imperative of addressing insulin resistance in the broader …