Esophageal cancer: priorities for prevention

DC Whiteman - Current Epidemiology Reports, 2014 - Springer
… It is hypothesized that the metabolic disturbances engendered by visceral fat [including
insulin resistance and increased production of adipocytokines and insulin-like growth factors (…

Autocrine stimulation by insulin-like growth factor I is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells

YC Liu, CM Leu, FH Wong, WS Fong, SC Chen… - Journal of biomedical …, 2002 - Springer
… role for IGF-I in esophageal cancer was implied. In this study, we further investigated the
biological significance of the IGF-I autocrine system in esophageal cancer. Our data showed the …

No Association Between IRS2 Gly1057Asp Polymorphism and Esophageal Cancer

İ Gülaçar, Z Kaya, N Almalı, C Ateş… - Van Sağlık Bilimleri …, 2021 - dergipark.org.tr
… We recruited 100 healthy controls and 70 esophageal cancer patients. In control group, …
Lack of association between insulin receptor substrate 2 rs1805097 polymorphism and the …

Association of insulin and insulin-like growth factors with Barrett's oesophagus

KB Greer, CL Thompson, L Brenner, B Bednarchik… - Gut, 2012 - gut.bmj.com
Insulin resistance (IR) was estimated based on Homeostatic Model Assessment (HOMA).27
This model estimates insulin resistance from basal insulin … plasma insulin concentration (μIU/…

Obesity and cancer, a case for insulin signaling

Y Poloz, V Stambolic - Cell death & disease, 2015 - nature.com
cancer is the development of insulin resistance (IR) and hyperinsulinemia. This review focuses
on defining the link between obesity, IR and cancer… 37% of esophageal cancer cases. A …

[HTML][HTML] Advances and challenges in the treatment of esophageal cancer

S He, J Xu, X Liu, Y Zhen - Acta Pharmaceutica Sinica B, 2021 - Elsevier
… Schematic diagram of molecular targeted therapy for esophageal cancer. Frequent genetic
alterations in key signaling pathways in esophageal cancer, involving insulin-like growth …

Carbohydrate consumption and esophageal cancer: an ecological assessment

CL Thompson, V Khiani, A Chak… - Official journal of the …, 2008 - journals.lww.com
esophageal cancer rates. This may not directly reflect individual food consumption and
esophageal cancer … intake, obesity, and insulin resistance in carcinogenesis, our study adds data …

Insulin/IGF-1 signaling is downregulated in Barrett's esophagus patients undergoing a moderate calorie and protein restriction program: a randomized 2-year trial

D Arcidiacono, A Zaramella, F Fabris… - Nutrients, 2021 - mdpi.com
… Hyperinsulinemia and insulin resistance may mediate cancer progression via the … in
esophageal cancer onset has been exhaustively studied in our surgically induced esophageal

The intracellular mechanism of insulin resistance in pancreatic cancer patients

J Liu, JA Knezetic, L Strömmer… - The Journal of …, 2000 - academic.oup.com
… the diabetic pancreatic cancer group. … cancer patients, but glycogen phosphorylase mRNA
levels were not significantly different. The insulin resistance associated with pancreatic cancer

Nutrition in peri-operative esophageal cancer management

E Steenhagen, JK van Vulpen… - Expert review of …, 2017 - Taylor & Francis
… stress response and potentially culminating in insulin resistance, hyperglycemia, and muscle
… carbohydrate treatment reduces postoperative insulin resistance but does not increase or …