[HTML][HTML] Genetics of insulin resistance and the metabolic syndrome

AE Brown, M Walker - Current cardiology reports, 2016 - Springer
… Large-scale genome-wide association studies have helped advance the identification of
common genetic variation associated with insulin resistance and the metabolic syndrome, and …

Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic syndrome and cardiovascular disease

DR Gable, SJ Hurel, SE Humphries - Atherosclerosis, 2006 - Elsevier
… and insulin resistance, and also insulin resistance and cardiovascular disease, is examined.
Variation in the adiponectin gene … The association of identified variants with human disease, …

[HTML][HTML] VDR gene variation and insulin resistance related diseases

F Han, Y Lv, L Gong, H Liu, Z Wan, L Liu - Lipids in health and disease, 2017 - Springer
… whether VDR Gene polymorphisms could predict insulin resistance on a large scale. … to
elucidate whether VDR Gene polymorphisms could predict insulin resistance on a large scale. …

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

JC Chambers, P Elliott, D Zabaneh, W Zhang, Y Li… - … genetics, 2008 - nature.com
We carried out a genome-wide association study (318,237 SNPs) for insulin resistance and
related phenotypes in 2,684 Indian Asians, with further testing in 11,955 individuals of Indian …

Fatty acid binding protein-2 gene variants and insulin resistance: gene and gene-environment interaction effects

EP Weiss, MD Brown, AR Shuldiner… - Physiological …, 2002 - journals.physiology.org
… , therefore, affect insulin sensitivity and glucose metabolism. … gene variants and their
association with insulin resistance … silent variants and those in the noncoding regions of the gene (…

Study of Genetic Variation in the STAT3 on Obesity and Insulin Resistance in Male Adults

TF Gianotti, S Sookoian, C Gemma, AL Burgueño… - …, 2008 - Wiley Online Library
gene for assessing obesity and insulin resistance susceptibility alleles, our results do not
support a major role for STAT3 variants in BMI and insulin resistance in our male population. …

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity

RA Scott, T Fall, D Pasko, A Barker, SJ Sharp… - Diabetes, 2014 - Am Diabetes Assoc
genetic variants as instruments for insulin resistance … of genetic scores with euglycemic-hyperinsulinemic
clamp– and oral glucose tolerance test–based measures of insulin resistance

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

AK Manning, MF Hivert, RA Scott, JL Grimsby… - … genetics, 2012 - nature.com
genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance
… ) and potential interactions between BMI and genetic variants. We applied a joint meta-…

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

K Hara, K Tobe, T Okada, H Kadowaki, Y Akanuma… - Diabetologia, 2002 - Springer
… in muscle and the opposite effect in the liver, and a functional study, such as gene-targeting …
, a genetic variation in the PGC-1 gene was found to be associated with insulin resistance. …

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

J Rung, S Cauchi, A Albrechtsen, L Shen… - … genetics, 2009 - nature.com
… common variants that only partially explain the genetic risk … located adjacent to the insulin
receptor substrate 1 gene (IRS1). … was associated with insulin resistance and hyperinsulinemia …