… of insulin-resistant individuals than in normal individuals (6, 13). In keeping with the concept
that mitochondrial deficiency causes insulin resistance… in muscle insulin resistance results in …

… In summary, mitochondrial “deficiency” is not merely a … The most common forms of human
skeletal muscle insulin resistance … Impairments in mitochondrial energetics have been linked to …

… Our primary aim is to broadly highlight how insulin deficiency in T1D and insulin resistance
… mitochondrial function, primarily in skeletal muscle. We also provide data on mitochondrial …

… the onset of the insulin resistance. It … mitochondrial deficiency precedes insulin resistance
in humans, because T2DM patients and obese insulin resistant individuals are insulin resistant …

… insulin resistance in classic and nonclassic insulin target tissues. Insulin resistance emanating
from mitochondrial … In fact, eNOS-deficient mice are insulin resistant and hypertensive and …

… in mitochondrial … mitochondrial defect in insulin-resistant individuals. Electron microscopic
studies have demonstrated morphological abnormalities in mitochondria in insulinresistant …

… However, it is unclear whether the reduced mitochondrial function is a primary or acquired …
in mitochondrial β-oxidation can cause insulin resistance, we studied mice with a deficiency of …

… to the theory that compromised mitochondrial oxidative function, … insulin resistance. Here,
we review the latest findings regarding the link between mitochondrial metabolism and insulin …

… linking mitochondrial dysfunction and insulin resistance, and review the potential for mitochondrial
targets as a … Thus, incretin deficiency is a likely contributor to progressive decreases in …

… mitochondrial function was more pronounced in the insulin-deficient state than in insulin
resistance… The modification of fatty acid composition of cardiac and mitochondrial membranes …